Enhanced therapeutic efficacy of biogenic nanosilver-conjugated thymol: In vitro and in vivo evaluation against emerging multi-drug resistant microbes

VP Ram, J Yasur, P Abishad, C Ramesh… - Journal of Drug Delivery …, 2023 - Elsevier
Phytochemicals and nanoparticles (NPs) despite having strong antibacterial activity, their
limited stability and safety prevent their widespread biomedical and environmental …

Antimicrobial efficacy of green synthesized nanosilver with entrapped cinnamaldehyde against multi-drug-resistant enteroaggregative Escherichia coli in Galleria …

V Prasastha Ram, J Yasur, P Abishad, V Unni… - Pharmaceutics, 2022 - mdpi.com
The global emergence of antimicrobial resistance (AMR) needs no emphasis. In this study,
the in vitro stability, safety, and antimicrobial efficacy of nanosilver-entrapped …

Characterization of the Antimicrobial Activities of Trichoplusia ni Cecropin A as a High-Potency Therapeutic against Colistin-Resistant Escherichia coli

H Lee, B Kim, M Kim, S Yoo, J Lee, E Hwang, Y Kim - Pharmaceutics, 2023 - mdpi.com
The spread of colistin-resistant bacteria is a serious threat to public health. As an alternative
to traditional antibiotics, antimicrobial peptides (AMPs) show promise against multidrug …

Galleria mellonella experimental model: advances and future directions

JC Junqueira, E Mylonakis, E Borghi - Pathogens and disease, 2021 - academic.oup.com
For the last 20 years, the greater wax moth Galleria mellonella has gathered widespread
interest in the scientific community as a model host. During this time, there has been an …

Preliminary Toxicity Evaluation of a Porphyrin Photosensitizer in an Alternative Preclinical Model

MC Malacarne, M Mastore, MB Gariboldi… - International Journal of …, 2023 - mdpi.com
In photodynamic therapy (PDT), a photosensitizer (PS) excited with a specific wavelength,
and in the presence of oxygen, gives rise to photochemical reactions that lead to cell …

Oncolytic avian reovirus-sensitized tumor infiltrating CD8+ T cells triggering immunogenic apoptosis in gastric cancer

YY Wu, FH Wu, IC Chen, TL Liao, M Munir… - Cell Communication and …, 2024 - Springer
Background Gastric cancer (GC) is a leading malignant disease in numerous countries,
including Taiwan with limited therapeutic options. Animal viruses including oncolytic avian …

Antibacterial efficacy of in‐house designed cell‐penetrating peptide against multi‐drug resistant strains of Salmonella Enteritidis and Salmonella Typhimurium

MAD Nishanth, S Bhoomika… - Environmental …, 2022 - Wiley Online Library
The in vitro antibacterial efficacy of an in‐house designed cell‐penetrating peptide (CPP)
variant of Cecropin A (1–7)‐Melittin (CAMA)(CAMA‐CPP) against the characterized multi …

[HTML][HTML] Octominin: An antimicrobial peptide with antibacterial and anti-inflammatory activity against carbapenem-resistant Escherichia coli both in vitro and in vivo

J Kong, Y Wang, Y Han, H Zhou, Z Huang… - Journal of Global …, 2023 - Elsevier
Objectives The emergence of carbapenem-resistant Escherichia coli (CREC) is a global
concern as its prevalence restricts treatment options and poses a considerable threat to …

Antimicrobial efficacy of chitosan encapsulated Cecropin-A (1–7)-melittin-cell-penetrating peptide against multi-drug-resistant Salmonella Enteritidis

DP Gourkhede, MAD Nishanth, VP Ram… - Journal of Drug Delivery …, 2022 - Elsevier
In wake of antimicrobial resistance (AMR), the present study evaluated the antimicrobial
efficacy of chitosan-encapsulated Cecropin-A (1–7)-melittin-cell penetrating peptide (ENC …

Lidocaine Modulates Cytokine Production and Enhances Anti-Tumor Immune Response in Gastric Cancer: Dual Effects on Normal Peripheral Blood Mononuclear …

YY Wu, MS Chen, IC Chen, FH Wu, TL Liao, HW Wen… - 2024 - preprints.org
Lidocaine, a commonly used local anesthetic, has demonstrated modulatory effects in
various cells. This study investigates the impact of lidocaine on cytokine production in …