Background Prolongation of the corrected QT (QTc) interval is a key issue for patients who
receive psychotropic medications. Such patients may have baseline clinical risk factors for …

Method We searched PubMed for pertinent literature on the risk of QTc prolongation and/or
TdP associated with commonly used psychotropic drugs. Results Thioridazine and …

Introduction: Despite more that 60 years of clinical experience, the effective use of lithium for
the treatment of mood disorder, in particular bipolarity, is in danger of becoming obsolete. In …

Psychotropics are among the most common causes of drug induced acquired long QT
syndrome. Blockage of Human ether-ago-go-related gene (HERG) potassium channel by …

Lithium, a monovalent cation, was first used for the treatment of mania in the 1940s. Half a
century into its use, the drug continues to be the preeminent choice for bipolar disorder with …

A number of different psychotropic agents have been associated with an increased risk of
cardiovascular disease, and these relationships have been difficult to interpret due to the …

Background. Lithium overdose primarily results in neurologic toxicity; however, cardiac
effects have also been reported. Our aim was to describe a large cohort of hospitalized …

Abstract Background Antipsychotic/Antidepressant use is a risk factor for QT interval (QT)
prolongation and sudden cardiac death. However, it is unclear which drugs are risk factors …

Mitochondria play an important role in myocardial tissue homeostasis; therefore,
deterioration in mitochondrial function will eventually lead to cardiomyocyte and endothelial …

(1) Background: Few studies have explored the impact of lithium intoxication on the heart.(2)
Methods: We examined electrocardiogram (ECG) changes associated with lithium …