Hyaluronic acid (HA) is a large non-sulfated glycosaminoglycan that is the main component
of the extracellular matrix (ECM). Because of its strong and diversified functions applied in …

Polysaccharides have attracted considerable attention in a broad range of applications in
recent years, which is due to their remarkable features such as biocompatibility …

Nanotechnology is an advanced field that has remarkable nutraceutical and food
applications. Phyto-bioactive compounds (PBCs) play critical roles in promoting health and …

Since it is known that hyaluronic acid contributes to soft tissue growth, elasticity, and scar
reduction, different strategies of producing HA have been explored in order to satisfy the …

Hyaluronic acid (HA) has a special position among glycosaminoglycans. As a major
component of the extracellular matrix (ECM). This simple, unbranched polysaccharide is …

Dry eye disease (DED) is a high prevalent multifactorial disease characterized by a lack of
homeostasis of the tear film which causes ocular surface inflammation, soreness, and visual …

Activatable polymeric nanosystems have attracted great interest, and their interactions with
endo–exogenous stimulations are highly vital for therapeutic efficacy, which urgently needs …

Introduction Triple-negative breast cancer (TNBC) is a highly aggressive subtype with a poor
prognosis. Current single-agent checkpoint therapy has limited effectiveness in TNBC …

Cytotoxic chemotherapy continues to be the main therapeutic option for patients with
metastatic breast cancer. Several studies have reported a significant association between …

Drug targeting of tumor cells is one of the great challenges in cancer therapy; nanoparticles
based on natural polymers represent valuable tools to achieve this aim. The ability to …