Climate change and cascading risks from infectious disease
JC Semenza, J Rocklöv, KL Ebi - Infectious diseases and therapy, 2022 - Springer
Climate change is adversely affecting the burden of infectious disease throughout the world,
which is a health security threat. Climate-sensitive infectious disease includes vector-borne …
which is a health security threat. Climate-sensitive infectious disease includes vector-borne …
Antimalarial drug discovery: Progress and approaches
Recent antimalarial drug discovery has been a race to produce new medicines that
overcome emerging drug resistance, whilst considering safety and improving dosing …
overcome emerging drug resistance, whilst considering safety and improving dosing …
[HTML][HTML] Safety and efficacy of a monoclonal antibody against malaria in Mali
K Kayentao, A Ongoiba, AC Preston… - … England Journal of …, 2022 - Mass Medical Soc
Background CIS43LS is a monoclonal antibody that was shown to protect against controlled
Plasmodium falciparum infection in a phase 1 clinical trial. Whether a monoclonal antibody …
Plasmodium falciparum infection in a phase 1 clinical trial. Whether a monoclonal antibody …
Malaria in 2022: Increasing challenges, cautious optimism
P Jagannathan, A Kakuru - Nature communications, 2022 - nature.com
Malaria cases and deaths remain unacceptably high and are resurgent in several settings,
though recent developments inspire optimism. This includes the approval of the world's first …
though recent developments inspire optimism. This includes the approval of the world's first …
Subcutaneous administration of a monoclonal antibody to prevent malaria
K Kayentao, A Ongoiba, AC Preston… - … England Journal of …, 2024 - Mass Medical Soc
Background Subcutaneous administration of the monoclonal antibody L9LS protected adults
against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal …
against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal …
The RTS, S malaria vaccine: Current impact and foundation for the future
JG Beeson, L Kurtovic, C Valim, KP Asante… - Science Translational …, 2022 - science.org
The RTS, S vaccine has recently been recommended for implementation as a childhood
vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of …
vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of …
Malaria vaccines: progress to date
DI Stanisic, MF Good - BioDrugs, 2023 - Springer
Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …
Current approaches to malaria vaccines
PE Duffy - Current opinion in microbiology, 2022 - Elsevier
Highlights•First malaria vaccine RTS, S induces anti-sporozoite antibodies to protect
children.•Whole-sporozoite vaccines induce T cells and antibodies and confer field …
children.•Whole-sporozoite vaccines induce T cells and antibodies and confer field …
Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose …
SC van der Boor, MJ Smit, SW van Beek… - The Lancet Infectious …, 2022 - thelancet.com
Background Malaria elimination requires interruption of the highly efficient transmission of
Plasmodium parasites by mosquitoes. TB31F is a humanised monoclonal antibody that …
Plasmodium parasites by mosquitoes. TB31F is a humanised monoclonal antibody that …
Seasonal vaccination with RTS, S/AS01E vaccine with or without seasonal malaria chemoprevention in children up to the age of 5 years in Burkina Faso and Mali: a …
A Dicko, JB Ouedraogo, I Zongo, I Sagara… - The Lancet Infectious …, 2024 - thelancet.com
Background Seasonal vaccination with the RTS, S/AS01 E vaccine combined with seasonal
malaria chemoprevention (SMC) prevented malaria in young children more effectively than …
malaria chemoprevention (SMC) prevented malaria in young children more effectively than …