A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans
J Dobbelaere, TY Su, B Erdi, A Schleiffer… - The EMBO …, 2023 - embopress.org
Cilia are cellular projections that perform sensory and motile functions in eukaryotic cells. A
defining feature of cilia is that they are evolutionarily ancient, yet not universally conserved …
defining feature of cilia is that they are evolutionarily ancient, yet not universally conserved …
In-cell structural insight into the stability of sperm microtubule doublet
L Tai, G Yin, X Huang, F Sun, Y Zhu - Cell Discovery, 2023 - nature.com
The propulsion for mammalian sperm swimming is generated by flagella beating.
Microtubule doublets (DMTs) along with microtubule inner proteins (MIPs) are essential …
Microtubule doublets (DMTs) along with microtubule inner proteins (MIPs) are essential …
Effect of α-tubulin acetylation on the doublet microtubule structure
Acetylation of α-tubulin at the lysine 40 residue (αK40) by αTAT1/MEC-17 acetyltransferase
modulates microtubule properties and occurs in most eukaryotic cells. Previous literatures …
modulates microtubule properties and occurs in most eukaryotic cells. Previous literatures …
Mechanisms of cilia regeneration in Xenopus multiciliated epithelium in vivo
VG Rao, V Subramanianbalachandar, MM Magaj… - bioRxiv, 2023 - biorxiv.org
Cilia regeneration is a physiological event, and while studied extensively in unicellular
organisms, it remains poorly understood in vertebrates. In this study, using Xenopus …
organisms, it remains poorly understood in vertebrates. In this study, using Xenopus …
[HTML][HTML] SUB-Immunogold-SEM reveals nanoscale distribution of submembranous epitopes
Electron microscopy paired with immunogold labeling is the most precise tool for protein
localization. However, these methods are either cumbersome, resulting in small sample …
localization. However, these methods are either cumbersome, resulting in small sample …
Ccdc66 regulates primary cilium stability, disassembly and signaling important for epithelial organization
J Deretic, S Cengiz-Emek, E Seyrek, EN Firat-Karalar - bioRxiv, 2024 - biorxiv.org
The primary cilium is a conserved, microtubule-based organelle that transduces signaling
pathways essential for development and homeostasis. It is a dynamic structure that …
pathways essential for development and homeostasis. It is a dynamic structure that …