The roles of both neuroinflammation and oxidative stress in the pathophysiology of epilepsy
have begun to receive considerable attention in recent years. However, these concepts are …

Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

Sulforaphane (SFN) is a naturally occurring compound found in cruciferous vegetables such
as broccoli and cauliflower. It has been widely studied for its potential as a neuroprotective …

Previously developed fluorophenyl-isoxazole-carboxamides derivatives were re-
synthesized and their scavenging activity against DPPH free radical and inhibitory activity …

Background Drug resistance is a particular problem in patients with temporal lobe epilepsy,
where seizures originate mainly from the hippocampus. Many of these epilepsies are …

Pyroptosis is a process of programmed cell death mediated by gasdermin (GSDM) found in
recent years. In the process of pyroptosis, caspase-1 or caspase-11/4/5 is activated, which …

Neurodegenerative diseases are neurological disorders that become more prevalent with
age, usually caused by damage or loss of neurons or their myelin sheaths, such as …

Abstract The NADPH Oxidase (NOX) enzymes are key producers of reactive oxygen species
(ROS) and consist of seven different isoforms, distributed across the tissues and cell types …

Epilepsy is a common neurological disease characterized by the enduring predisposition of
the brain to generate seizures. Among the recognized causes, a role played by the gut …

Background Epilepsy affects over 65 million people worldwide and significantly burdens
patients, caregivers, and society. Drug-resistant epilepsy occurs in approximately 30% of …