Role of fibroblasts and myofibroblasts on the pathogenesis and treatment of pelvic organ prolapse

Z Guler, JP Roovers - Biomolecules, 2022 - mdpi.com
Pelvic organ prolapse (POP) is a multifactorial connective tissue disorder caused by
damage to the supportive structures of the pelvic floor, leading to the descent of pelvic …

International guidelines for groin hernia management

Hernia, 2018 - Springer
Introduction Worldwide, more than 20 million patients undergo groin hernia repair annually.
The many different approaches, treatment indications and a significant array of techniques …

Design, mechanical and degradation requirements of biodegradable metal mesh for pelvic floor reconstruction

Z Mardina, J Venezuela, C Maher, Z Shi… - Biomaterials …, 2022 - pubs.rsc.org
Pelvic organ prolapse is the herniation of surrounding tissue and organs into the vagina
and/or rectum and is a result of the weakening of pelvic floor muscles, connective tissue, and …

Modeling the flow behavior and flow rate of medium viscosity alginate for scaffold fabrication with a three-dimensional bioplotter

M Sarker, XB Chen - Journal of Manufacturing …, 2017 - asmedigitalcollection.asme.org
Tissue regeneration with scaffolds has proven promising for the repair of damaged tissues
or organs. Dispensing-based printing techniques for scaffold fabrication have drawn …

Mesh deformation: A mechanism underlying polypropylene prolapse mesh complications in vivo

KM Knight, GE King, SL Palcsey, A Suda, R Liang… - Acta biomaterialia, 2022 - Elsevier
Polypropylene meshes used in pelvic organ prolapse (POP) repair are hampered by
complications. Most POP meshes are highly unstable after tensioning ex vivo, as evidenced …

Roadmap on biomaterials for women's health

K Fogg, NH Tseng, SR Peyton… - Journal of Physics …, 2022 - iopscience.iop.org
The application of engineering tools and techniques to studying women's health, including
biomaterials-based approaches, is a research field experiencing robust growth. Biomaterials …

Exploring the basic science of prolapse meshes

R Liang, K Knight, S Abramowitch… - Current Opinion in …, 2016 - journals.lww.com
Exploring the basic science of prolapse meshes : Current Opinion in Obstetrics and Gynecology
Exploring the basic science of prolapse meshes : Current Opinion in Obstetrics and Gynecology …

Lengthwise regional mechanics of the human aneurysmal ascending thoracic aorta

SA Tarraf, B Kramer, E Vianna, C Gillespie, E Germano… - Acta biomaterialia, 2023 - Elsevier
The prognosis of patients undergoing emergency endovascular repair of ascending thoracic
aortic aneurysm (ATAA) depends on defect location, with root disease bearing worse …

A novel characterisation approach to reveal the mechano–chemical effects of oxidation and dynamic distension on polypropylene surgical mesh

NTH Farr, S Roman, J Schäfer, A Quade, D Lester… - RSC …, 2021 - pubs.rsc.org
Polypropylene (PP) surgical mesh, used successfully for the surgical repair of abdominal
hernias, is associated with serious clinical complications when used in the pelvic floor for …

Mesh induced fibrosis: the protective role of T regulatory cells

AM Artsen, M Rytel, R Liang, GE King, L Meyn… - Acta biomaterialia, 2019 - Elsevier
Polypropylene mesh is widely used in urogynecologic surgery, but complications rates (pain
and exposure) approach 10%. Emerging evidence implicates the adaptive immune system …