This study proposes a review on hyaluronic acid (HA) known as hyaluronan or hyaluronate
and its derivates and their application in cosmetic formulations. HA is a glycosaminoglycan …

Chondrogenesis is a highly coordinated event in embryo development, adult homeostasis,
and repair of the vertebrate cartilage. Fate decisions and differentiation of chondrocytes …

Osteoarthritis (OA) is a common joint disease characterized by progressive loss of cartilage
and reduction in lubricating synovial fluid, which lacks effective treatments currently. Here …

Objectives Understanding the molecular mechanisms underlying human cartilage
degeneration and regeneration is helpful for improving therapeutic strategies for treating …

The role of native (not culture-expanded) joint-resident mesenchymal stem cells (MSCs) in
the repair of joint damage in osteoarthritis (OA) is poorly understood. MSCs differ from bone …

The development of interdisciplinary biomedical engineering brings significant
breakthroughs to the field of cartilage regeneration. However, cartilage defects are …

In the absence of timely and proper treatments, injuries to articular cartilage (AC) can lead to
cartilage degeneration and ultimately result in osteoarthritis. Regenerative medicine and …

Joint distraction, the prolonged mechanical separation of the bones at a joint, has emerged
as a joint-preserving treatment for end-stage osteoarthritis, with the gradually growing …

Background Trauma-or osteoarthritis-related cartilage damage resulted in functional decline
of joints and heavy burden of public health. Recently, the reparative role of mesenchymal …

Utilization of joint-resident mesenchymal stem cells (MSC) to repair articular cartilage is a
promising strategy in osteoarthritis (OA) therapy but remains a considerable research …