Pumps for microfluidic cell culture
CK Byun, K Abi‐Samra, YK Cho, S Takayama - Electrophoresis, 2014 - Wiley Online Library
In comparison to traditional in vitro cell culture in Petri dishes or well plates, cell culture in
microfluidic‐based devices enables better control over chemical and physical environments …
microfluidic‐based devices enables better control over chemical and physical environments …
A review on microfluidics manipulation of the extracellular chemical microenvironment and its emerging application to cell analysis
Spatiotemporal manipulation of extracellular chemical environments with simultaneous
monitoring of cellular responses plays an essential role in exploring fundamental biological …
monitoring of cellular responses plays an essential role in exploring fundamental biological …
VEGFR1 promotes cell migration and proliferation through PLCγ and PI3K pathways
JC Weddell, S Chen, PI Imoukhuede - NPJ systems biology and …, 2017 - nature.com
The ability to control vascular endothelial growth factor (VEGF) signaling offers promising
therapeutic potential for vascular diseases and cancer. Despite this promise, VEGF-targeted …
therapeutic potential for vascular diseases and cancer. Despite this promise, VEGF-targeted …
Temporal bias: time-encoded dynamic GPCR signaling
M Grundmann, E Kostenis - Trends in pharmacological sciences, 2017 - cell.com
Evidence suggests that cells can time-encode signals for secure transport and perception of
information, and it appears that this dynamic signaling is a common principle of nature to …
information, and it appears that this dynamic signaling is a common principle of nature to …
Logic digital fluidic in miniaturized functional devices: Perspective to the next generation of microfluidic lab‐on‐chips
Q Zhang, M Zhang, L Djeghlaf, J Bataille… - …, 2017 - Wiley Online Library
Microfluidics has emerged following the quest for scale reduction inherent to micro‐and
nanotechnologies. By definition, microfluidics manipulates fluids in small channels with …
nanotechnologies. By definition, microfluidics manipulates fluids in small channels with …
A sharp-edge-based acoustofluidic chemical signal generator
Resolving the temporal dynamics of cell signaling pathways is essential for regulating
numerous downstream functions, from gene expression to cellular responses. Mapping …
numerous downstream functions, from gene expression to cellular responses. Mapping …
Integrated perfusion and separation systems for entrainment of insulin secretion from islets of Langerhans
A microfluidic system was developed to investigate the entrainment of insulin secretion from
islets of Langerhans to oscillatory glucose levels. A gravity-driven perfusion system was …
islets of Langerhans to oscillatory glucose levels. A gravity-driven perfusion system was …
Entrainment to periodic initiation and transition rates in a computational model for gene translation
Periodic oscillations play an important role in many biomedical systems. Proper functioning
of biological systems that respond to periodic signals requires the ability to synchronize with …
of biological systems that respond to periodic signals requires the ability to synchronize with …
A Markovian approach to the optimal demodulation of diffusion-based molecular communication networks
CT Chou - IEEE Transactions on Communications, 2015 - ieeexplore.ieee.org
In a diffusion-based molecular communication network, transmitters and receivers
communicate by using signalling molecules (or ligands) in a fluid medium. This paper …
communicate by using signalling molecules (or ligands) in a fluid medium. This paper …
Silibinin (Milk Thistle) potentiates ethanol-dependent hepatocellular carcinoma progression in male mice
E Brandon-Warner, AL Eheim, DM Foureau, TL Walling… - Cancer letters, 2012 - Elsevier
Hepatocellular carcinoma (HCC) is a global health burden with limited treatment options
and poor prognosis. Silibinin, an antioxidant derived from the Milk Thistle plant (Silybum …
and poor prognosis. Silibinin, an antioxidant derived from the Milk Thistle plant (Silybum …