Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly
throughout the world and threaten to become untreatable. The origins of resistance are …

Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

Various antibiotics have been used in the treatment of cancers, via their anti-proliferative,
pro-apoptotic and anti-epithelial-mesenchymal-transition (EMT) capabilities. However …

Given the increase in antibiotic-resistant bacteria, alongside the alarmingly low rate of newly
approved antibiotics for clinical usage, we are on the verge of not having effective treatments …

Successful treatment of tuberculosis (TB) can be hampered by Mycobacterium tuberculosis
populations that are temporarily able to survive antibiotic pressure in the absence of drug …

The drug discovery process starts with identification of a disease-modifying target. This
critical step traditionally begins with manual investigation of scientific literature and …

Microorganisms possess a variety of survival mechanisms, including the production of
antimicrobials that function to kill and/or inhibit the growth of competing microorganisms …

The potential for the build-up of resistance to a particular antibiotic endangers its therapeutic
application over time. In recent decades, antibiotic resistance has become one of the most …

Multidrug-resistant (MDR) pathogens are currently causing serious problems globally in the
medical setting. Improper and extensive usage of antibiotics results in a selective pressure …

Introduction: The development of new antimicrobials has become an urgent priority because
of a global challenge emerging from the rise of antimicrobial resistant pathogens. Areas …