Comprehensive insights into glioblastoma multiforme: drug delivery challenges and multimodal treatment strategies

A Dhiman, D Rana, D Benival, K Garkhal - Therapeutic Delivery, 2024 - Taylor & Francis
Glioblastoma multiforme (GBM) is one of the most common and malignant brain tumors, with
a high prevalence in elderly population. Most chemotherapeutic agents fail to reach the …

Progress in physiologically based pharmacokinetic-pharmacodynamic models of amino acids in humans

TJ McColl, DC Clarke - Current Opinion in Clinical Nutrition & …, 2024 - journals.lww.com
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Synthesis, molecular modeling Insights, and anticancer assessment of novel polyfunctionalized Pyridine congeners

MG Abouelenein, AA El-Rashedy, HM Awad… - Bioorganic …, 2023 - Elsevier
The present study describes synthesizing a novel series of polyfunctionalized pyridine
congeners 1–18 and assessed for cytotoxic efficacies versus HCT-116, MCF-7, and HepG-2 …

[PDF][PDF] A New Reaction of Togni Reagent II: α-C–H Ester-Functionalization of Tertiary Amides

MIH Khan, J Yang, SJ Kim, HV Le - 2022 - chemrxiv.org
Togni reagent II is a synthetically useful hypervalent iodine reagent for direct
trifluoromethylation. Herein, we report a new reaction of Togni reagent II: α-C–H ester …