Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare

P Suravajhala, LJA Kogelman… - Genetics Selection …, 2016 - Springer
In the past years, there has been a remarkable development of high-throughput omics (HTO)
technologies such as genomics, epigenomics, transcriptomics, proteomics and …

Applied animal genomics: results from the field

AL Van Eenennaam, KA Weigel… - Annu. Rev. Anim …, 2014 - annualreviews.org
Genomic selection (GS) is the use of statistical methods to estimate the genetic merit of a
genotyped animal based on prediction equations derived from large ancestral populations …

Genomic selection: a paradigm shift in animal breeding

T Meuwissen, B Hayes, M Goddard - Animal frontiers, 2016 - academic.oup.com
Traditional marker-assisted selection (MAS) did not result in a widespread use of DNA
information in animal breeding. The main reason was that the traits of interest in livestock …

[HTML][HTML] Genomic selection for producer-recorded health event data in US dairy cattle

KLP Gaddis, JB Cole, JS Clay, C Maltecca - Journal of Dairy Science, 2014 - Elsevier
Emphasizing increased profit through increased dairy cow production has revealed a
negative relationship of production with fitness and health traits. Decreased cow health can …

[HTML][HTML] Symposium review: Single-step genomic evaluations in dairy cattle

EA Mäntysaari, M Koivula, I Strandén - Journal of dairy science, 2020 - Elsevier
During the last decade, genomic selection has revolutionized dairy cattle breeding. For
example, Nordic dairy cows (Denmark, Finland, and Sweden) born in 2018 were> 90% sired …

Go with the flow—biology and genetics of the lactation cycle

EM Strucken, YCSM Laurenson… - Frontiers in genetics, 2015 - frontiersin.org
Lactation is a dynamic process, which evolved to meet dietary demands of growing
offspring. At the same time, the mother's metabolism changes to meet the high requirements …

[HTML][HTML] A single-step genomic model with direct estimation of marker effects

Z Liu, ME Goddard, F Reinhardt, R Reents - Journal of Dairy Science, 2014 - Elsevier
Compared with the currently widely used multi-step genomic models for genomic evaluation,
single-step genomic models can provide more accurate genomic evaluation by jointly …

[HTML][HTML] Invited review: Advances and applications of random regression models: From quantitative genetics to genomics

HR Oliveira, LF Brito, DAL Lourenco, FF Silva… - Journal of dairy …, 2019 - Elsevier
An important goal in animal breeding is to improve longitudinal traits; that is, traits recorded
multiple times during an individual's lifetime or physiological cycle. Longitudinal traits were …

[HTML][HTML] Methods for genomic evaluation of a relatively small genotyped dairy population and effect of genotyped cow information in multiparity analyses

DAL Lourenco, I Misztal, S Tsuruta, I Aguilar… - Journal of dairy …, 2014 - Elsevier
Methods for genomic prediction were evaluated for an Israeli Holstein dairy population of
713,686 cows and 1,305 progeny-tested bulls with genotypes. Inclusion of genotypes of 343 …

[HTML][HTML] Single-step genomic evaluation using multitrait random regression model and test-day data

M Koivula, I Strandén, J Pösö, GP Aamand… - Journal of Dairy …, 2015 - Elsevier
The objectives of this study were to evaluate the feasibility of use of the test-day (TD) single-
step genomic BLUP (ssGBLUP) using phenotypic records of Nordic Red Dairy cows. The …