Inflammatory bowel diseases (IBD), comprising Crohn's disease and ulcerative colitis, are
systemic and multifaceted disorders which affect other organs in addition to the …

A prospective study suggests that the risk of liver fibrosis with methotrexate treatment has
been overestimated. The findings suggest the need to reconsider the intensive strategies …

Yes-associated protein (YAP) is an essential driver of hepatocellular carcinoma (HCC)
progression and the ubiquitin-proteasome system controls its abundance. However, the role …

Diagnosing and treating liver fibrosis is a challenging yet crucial endeavor due to its
complex pathogenesis and risk of deteriorating into cirrhosis, liver failure, and even hepatic …

Introduction Cecropin AD (CAD), a renowned antimicrobial peptide, has shown promising
potential in treating various bacterial infections. This study investigates the protective effects …

Editorial compared with risk factors for chronic liver disease. Ironically, the proportion of
patients with cirrhosis was higher in methotrexate-naive patients, who had higher alcohol …

Psoriasis is a chronic and multifactorial skin disease which is caused by inflammatory
infiltrates, keratinocyte hyperproliferation, and accumulation of immune cells. As part of the …

Background There are established risk factors for liver fibrosis (LF), but data on the impact of
methotrexate on LF in patients with psoriasis are lacking. Objectives This cross-sectional …

Introduction There are conflicting findings on the link between liver fibrosis and cumulative
methotrexate dosages. We aimed to determine the frequency of liver fibrosis in rheumatoid …

Ревматоидный артрит (РА)-наиболее частое иммуновоспалительное (аутоиммунное)
ревматическое заболевание, характеризующееся хроническим эрозивным артритом и …