In his seminal work, 1 Rolf Huisgen defined 1, 3-dipolar cycloadditions as “1, 3-Dipole, abc,
must be defined, such that atom a posseses an electron sextet, that is, an incomplete …

A domino reaction has been defined by Tietze as a reaction involving two or more bond-
forming transformations that take place under the same reaction conditions, without adding …

The preparation of urea by Wöhler constituted a landmark achievement in organic chemistry,
and it laid the ground for the early days of target-oriented organic synthesis. 1 Since then …

Heterocyclic synthesis involving transition metal complexes has become of common use in
the past decade because a transition-metal-catalyzed reaction can directly build …

Silver and gold salts and complexes mainly act as soft and carbophilic Lewis acids even if
their use as σ-activators has been rarely reported. Recently, transformations involving Au …

Due to their numerous reactivity modes, α‐aminonitriles represent versatile and valuable
building blocks in organic total synthesis. Since their discovery by Adolph Strecker in 1850 …

A silver (I)/ThioClickFerrophos complex catalyzed the highly endo-selective asymmetric 1, 3-
dipolar cycloaddition reaction of methyl N-benzylideneglycinate (the source of azomethine …

In this tutorial review, which should be of general interest to synthetic organic chemists at
large, recent progress in the total synthesis of the tetrahydroisoquinoline antitumor …

Pyrrolidines are privileged substructures of numerous bioactive natural products and drugs.
How to synthesize these important synthetic targets in a more efficient manner is a hot …

An improved protocol for the construction of enantioenriched pyrrolidine, indoline, and
piperidine rings using an organocatalyzed, intramolecular heteroatom Michael addition is …