Acute lymphoblastic leukaemia (ALL) occurs at all ages but is the most common cancer of
childhood. The current treatment of paediatric ALL is highly successful with up to 90 …

Single nucleotide polymorphism arrays (SNP-A) have recently been widely applied as a
powerful karyotyping tool in numerous translational cancer studies. SNP-A complements …

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using
whole-genome, exome and transcriptome sequencing of 2,754 childhood patients with ALL …

Background Chromosomal abnormalities in childhood acute lymphoblastic leukaemia are
well established disease markers and indicators of outcomes. However, the long-term …

We report 2 novel, cryptic chromosomal abnormalities in precursor B-cell acute
lymphoblastic leukemia (BCP-ALL): a translocation, either t (X; 14)(p22; q32) or t (Y; …

The biology and outcome of adult T-cell acute lymphoblastic leukemia are poorly
understood. We present here the clinical and biologic features of 356 patients treated …

Prospective data on the value of allogeneic hematopoietic stem cell transplantation
(alloHSCT) in Philadelphia chromosome–positive (Ph+) acute lymphoblastic leukemia (ALL) …

Using data from a genome-wide association study of 907 individuals with childhood acute
lymphoblastic leukemia (cases) and 2,398 controls and with validation in samples totaling …

Abstract High hyperdiploidy (51–67 chromosomes) is the most common cytogenetic
abnormality pattern in childhood B‐cell precursor acute lymphoblastic leukemia (ALL) …

Half of prostate cancers harbor gene fusions between TMPRSS2 and members of the ETS
transcription factor family. To date, little is known about the presence of non-ETS fusion …