Gold nanoparticles in cancer treatment

K Sztandera, M Gorzkiewicz… - Molecular …, 2018 - ACS Publications
Colloidal gold has been studied for its potential application in medicine for centuries.
However, synthesis and evaluation of various gold nanoparticles have only recently been …

Dendrimers in biomedical applications—reflections on the field

S Svenson, DA Tomalia - Advanced drug delivery reviews, 2012 - Elsevier
The formation of particulate systems with well-defined sizes and shapes is of eminent
interest in certain medical applications such as drug delivery, gene transfection, and …

Delivery of siRNA therapeutics: barriers and carriers

J Wang, Z Lu, MG Wientjes, JLS Au - The AAPS journal, 2010 - Springer
RNA interference is a naturally occurring endogenous regulatory process where short
double-stranded RNA causes sequence-specific posttranscriptional gene silencing. Small …

Dendrimers in drug research

U Boas, PMH Heegaard - Chemical Society Reviews, 2004 - pubs.rsc.org
Dendrimers are versatile, derivatisable, well-defined, compartmentalised chemical polymers
with sizes and physicochemical properties resembling those of biomolecules eg proteins …

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …

Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

AJL Villaraza, A Bumb, MW Brechbiel - Chemical reviews, 2010 - ACS Publications
Magnetism in medicine has had a long and interesting history. In the 10th century AD,
Egyptian physician and philosopher Avicenna prescribed a grain of magnetite dissolved in …

Dendrimers: emerging polymers for drug-delivery systems

BK Nanjwade, HM Bechra, GK Derkar, FV Manvi… - European Journal of …, 2009 - Elsevier
Dendrimers are new class of polymeric materials. It is generally described as a
macromolecule, which is characterized by its extensively branched 3D structure that …

Dendrimers in medicine: therapeutic concepts and pharmaceutical challenges

L Wu, M Ficker, JB Christensen… - Bioconjugate …, 2015 - ACS Publications
Dendrimers are three-dimensional macromolecular structures originating from a central core
molecule and surrounded by successive addition of branching layers (generation). These …

Dendrimers as versatile platform in drug delivery applications

S Svenson - European Journal of Pharmaceutics and …, 2009 - Elsevier
About forty percent of newly developed drugs are rejected by the pharmaceutical industry
and will never benefit a patient because of poor bioavailability due to low water solubility …

Dendrimer–drug interactions

A D'Emanuele, D Attwood - Advanced drug delivery reviews, 2005 - Elsevier
The interaction between drugs and dendrimers is reviewed with particular reference to the
entrapment of drugs within the dendrimer architecture and the electrostatic and covalent …