Plant lipids: Key players of plasma membrane organization and function

AM Cassim, P Gouguet, J Gronnier, N Laurent… - Progress in Lipid …, 2019 - Elsevier
The plasma membrane (PM) is the biological membrane that separates the interior of all
cells from the outside. The PM is constituted of a huge diversity of proteins and lipids. In this …

[HTML][HTML] Biosynthesis and the roles of plant sterols in development and stress responses

Y Du, X Fu, Y Chu, P Wu, Y Liu, L Ma, H Tian… - International Journal of …, 2022 - mdpi.com
Plant sterols are important components of the cell membrane and lipid rafts, which play a
crucial role in various physiological and biochemical processes during development and …

[HTML][HTML] Identification of natural RORγ ligands that regulate the development of lymphoid cells

FR Santori, P Huang, SA van de Pavert, EF Douglass… - Cell metabolism, 2015 - cell.com
Mice deficient in the nuclear hormone receptor RORγt have defective development of
thymocytes, lymphoid organs, Th17 cells, and type 3 innate lymphoid cells. RORγt binds to …

An update on the function and regulation of methylerythritol phosphate and mevalonate pathways and their evolutionary dynamics

X Pu, X Dong, Q Li, Z Chen, L Liu - Journal of Integrative Plant …, 2021 - Wiley Online Library
Isoprenoids are among the largest and most chemically diverse classes of organic
compounds in nature and are involved in the processes of photosynthesis, respiration …

[HTML][HTML] Another level of complex-ity: The role of metabolic channeling and metabolons in plant terpenoid metabolism

M Gutensohn, E Hartzell, N Dudareva - Frontiers in Plant Science, 2022 - frontiersin.org
Terpenoids constitute one of the largest and most diverse classes of plant metabolites. While
some terpenoids are involved in essential plant processes such as photosynthesis …

Modulation of Arabidopsis root growth by specialized triterpenes

Y Bai, P Fernández‐Calvo, A Ritter, AC Huang… - New …, 2021 - Wiley Online Library
Plant roots are specialized belowground organs that spatiotemporally shape their
development in function of varying soil conditions. This root plasticity relies on intricate …

Genomic population structure and local adaptation of the wild strawberry Fragaria nilgerrensis

Y Hu, C Feng, L Yang, PP Edger… - Horticulture Research, 2022 - academic.oup.com
The crop wild relative Fragaria nilgerrensis is adapted to a variety of diverse habitats across
its native range in China. Thus, discoveries made in this species could serve as a useful …

Contributions of both ATP-binding cassette transporter and Cyp51A proteins are essential for azole resistance in Aspergillus fumigatus

S Paul, D Diekema… - Antimicrobial Agents and …, 2017 - Am Soc Microbiol
While azole drugs targeting the biosynthesis of ergosterol are effective antifungal agents,
their extensive use has led to the development of resistant organisms. Infections involving …

[HTML][HTML] Diatoms synthesize sterols by inclusion of animal and fungal genes in the plant pathway

C Gallo, S Landi, G d'Ippolito, G Nuzzo, E Manzo… - Scientific reports, 2020 - nature.com
Diatoms are ubiquitous microalgae that have developed remarkable metabolic plasticity and
gene diversification. Here we report the first elucidation of the complete biosynthesis of …

[HTML][HTML] The cholesterol biosynthesis enzyme FAXDC2 couples Wnt/β-catenin to RTK/MAPK signaling

B Madan, SR Wadia, S Patnaik… - The Journal of …, 2024 - Am Soc Clin Investig
Wnts, cholesterol, and MAPK signaling are essential for development and adult
homeostasis. Here, we report that fatty acid hydroxylase domain containing 2 (FAXDC2), a …