Potential applications for antiviral therapy and prophylaxis in bovine medicine
BW Newcomer, PH Walz, MD Givens - Animal health research …, 2014 - cambridge.org
Viral disease is one of the major causes of financial loss and animal suffering in today's
cattle industry. Increases in global commerce and average herd size, urbanization, vertical …
cattle industry. Increases in global commerce and average herd size, urbanization, vertical …
Identification of short hairpin RNA targeting foot-and-mouth disease virus with transgenic bovine fetal epithelium cells
H Wang, J Wu, X Liu, H He, F Ding, H Yang, L Cheng… - 2012 - journals.plos.org
Background Although it is known that RNA interference (RNAi) targeting viral genes protects
experimental animals, such as mice, from the challenge of Foot-and-mouth disease virus …
experimental animals, such as mice, from the challenge of Foot-and-mouth disease virus …
Multiple microRNAs targeted to internal ribosome entry site against foot-and-mouth disease virus infection in vitro and in vivo
Y Chang, Y Dou, H Bao, X Luo, X Liu, K Mu, Z Liu… - Virology journal, 2014 - Springer
Background Foot-and-mouth disease virus (FMDV) causes a severe vesicular disease in
domestic and wild cloven-hoofed animals. Because of the limited early protection induced …
domestic and wild cloven-hoofed animals. Because of the limited early protection induced …
[HTML][HTML] Multi-resistance strategy for viral diseases and in vitro short hairpin RNA verification method in pigs
J Oh, K Choi, C Lee - Asian-Australasian journal of animal …, 2017 - pmc.ncbi.nlm.nih.gov
Objective Foot and mouth disease (FMD) and porcine reproductive and respiratory
syndrome (PRRS) are major diseases that interrupt porcine production. Because they are …
syndrome (PRRS) are major diseases that interrupt porcine production. Because they are …
Lentviral-mediated RNAi to inhibit target gene expression of the porcine integrin αv subunit, the FMDV receptor, and against FMDV infection in PK-15 cells
J Luo, J Du, S Gao, G Zhang, J Sun, G Cong, J Shao… - Virology journal, 2011 - Springer
Background shRNA targeting the integrin αv subunit, which is the foot-and-mouth disease
virus (FMDV) receptor, plays a key role in virus attachment to susceptible cells. We …
virus (FMDV) receptor, plays a key role in virus attachment to susceptible cells. We …
Adenovirus-vectored shRNAs targeted to the highly conserved regions of VP1 and 2B in tandem inhibits replication of foot-and-mouth disease virus both in vitro and in …
YF Xu, HY Shen, MQ Zhao, LJ Chen, YG Li… - Journal of virological …, 2012 - Elsevier
Foot-and-mouth disease is a highly contagious and economically important disease of
cloven-hoofed animals. RNA interference (RNAi) can be used as a rapid and specific …
cloven-hoofed animals. RNA interference (RNAi) can be used as a rapid and specific …
[HTML][HTML] Bovine fetal epithelium cells expressing shRNA targeting viral VP1 gene resisted against foot-and-mouth disease virus
H Wang, X Liu, J Wu, G Wu, L Yu, C He, H Yang, W Xie… - Virology, 2013 - Elsevier
RNAi could protect experimental animals from Foot-and-mouth disease virus (FMDV), but
pivotal issue is delivery of RNAi. In this study, shRNA recombinant lentiviral plasmid RNAi …
pivotal issue is delivery of RNAi. In this study, shRNA recombinant lentiviral plasmid RNAi …
Applications of RNA interference-based gene silencing in animal agriculture
CR Long, KJ Tessanne… - Reproduction, Fertility and …, 2009 - CSIRO Publishing
Classical genetic selection, recently aided by genomic selection tools, has been successful
in achieving remarkable progress in livestock improvement. However, genetic selection has …
in achieving remarkable progress in livestock improvement. However, genetic selection has …
[HTML][HTML] 慢病毒介导siRNA 抑制O 型口蹄疫病毒ON 株病毒复制
齐兴财， 秦晓东， 甘晓丽， 张淑敏， 马友记， 李志勇 - 畜牧兽医学报, 2018 - html.rhhz.net
探究RNA 干扰(RNA interference, RNAi) 技术对口蹄疫病毒复制的抑制作用, 本研究选取O
型口蹄疫病毒ON 株, 以ON 株口蹄疫病毒3C, 3D, VP1 蛋白基因作为靶基因 …
型口蹄疫病毒ON 株, 以ON 株口蹄疫病毒3C, 3D, VP1 蛋白基因作为靶基因 …