Many management strategies exist for neuroendocrine liver metastases. These strategies
range from surgery to ablation with various interventional radiology procedures, and include …

Pulmonary neuroendocrine tumors (NETs) are traditionally described as comprising a
spectrum of neoplasms, ranging from low grade typical carcinoids (TCs) via the intermediate …

Neuroendocrine tumours (NETs) originate in tissues that contain cells derived from the
embryonic neural crest, neuroectoderm and endoderm. Thus, NETs occur at many sites in …

We morphometrically evaluated 5-μm H&E-stained sections from 28 surgically resected high-
grade pulmonary neuroendocrine neoplasms, including 16 small cell lung carcinomas …

Background: Lung cancer is the leading cause of cancer-related deaths worldwide. The
typical and atypical carcinoid (TC and AC), the large-cell neuroendocrine carcinoma …

Neuroendocrine neoplasms (NENs) are a diverse group of malignancies with a shared
phenotype but varying prognosis and response to current treatments. Based on their …

p53 is a well-known tumor suppressor gene and one of the most extensively studied genes
in cancer research. p53 functions largely as a transcription factor and can trigger a variety of …

Small molecular weight GTPases (small G proteins) are essential in the transduction of
signals from different plasma membrane receptors. Due to their endogenous GTP …

Neuroendocrine tumors of the lung continue to be difficult nosologic and diagnostic
problems, centering on the time-honored terms of “carcinoid,”“atypical carcinoid,” and “small …

The BRAF gene, one of the human isoforms of RAF, is activated by ras, leading to
cooperative effects in cells responsive to growth factor signals. We studied the frequency of …