Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

In a state of oxidative stress, there is an increase of reactive species, which induce an
altered intracellular signaling, leading to dysregulation of the inflammatory response. The …

Parkinson's disease (PD) is the second most common neurodegenerative disorder which
affects 6.1 million people worldwide. The neuropathological hallmarks include the loss of …

Dopamine is derived from an amino acid, phenylalanine, which must be obtained through
the diet. Dopamine, known primarily to be a neurotransmitter involved in almost any higher …

Implantable biosensors are valuable scientific tools for basic neuroscience research and
clinical applications. Neurotechnologies provide direct readouts of neurological signal and …

Brain metastasis (BrM) is the most common form of brain cancer, characterized by
neurologic disability and an abysmal prognosis. Unfortunately, our understanding of the …

Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …

Background Parkinson's disease (PD) affects an estimated 7 to 10 million people worldwide,
and only symptomatic treatments are presently available to relieve the consequences of …

Neurodegenerative diseases of the central nervous system (CNS) are characterized by
progressive neuronal death and neurological dysfunction, leading to increased disability …

Dopamine (DA) is one of the major neurotransmitters and participates in a number of
functions such as motor coordination, emotions, memory, reward mechanism …