Viruses use cell machinery to replicate their genome and produce viral proteins. For this
reason, several intracellular factors, including the redox state, might directly or indirectly …

The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel severe acute
respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2). Here, we review the …

Early reports indicate an association between the severity of the COVID-19 infection and the
widespread 25-hydroxy vitamin D deficiency known to exist in populations around the world …

Host-directed therapy using drugs that target cellular pathways required for virus lifecycle or
its clearance might represent an effective approach for treating infectious diseases …

Background An overdose of acetaminophen (APAP), the main cause of acute liver failure
(ALF), induces oxidative stress that ultimately causes mitochondrial impairment and …

During inflammatory processes, immunocompetent cells are exposed to substantial amounts
of free radicals and toxic compounds. Glutathione is a cysteine-containing tripeptide that is …

The SARS‐CoV‐2 life cycle is strictly dependent on the environmental redox state that
influences both virus entry and replication. A reducing environment impairs the binding of …

We report the synthesis, chemical properties, and disulfide bond-reducing performance of a
dithiol called NACMEAA, conceived as a hybrid of two biologically relevant thiols: cysteine …

Simple Summary Oxidative stress negatively affects maternal health and fetal development.
Catalase (CAT) is an oxidoreductase enzyme that catalyzes the decomposition of hydrogen …

Aims The well-documented relationship between sperm oxidation and male infertility
strongly encourages the development of assays for reactive oxygen species detection in …