Diabetic nephropathy: new insights into established therapeutic paradigms and novel molecular targets

D Sharma, P Bhattacharya, K Kalia, V Tiwari - Diabetes Research and …, 2017 - Elsevier
Diabetic nephropathy is one of the most prevalent microvascular complication in patients
suffering from diabetes and is reported to be the major cause of renal failure when …

Protective effects of pomegranate (Punica granatum) and its main components against natural and chemical toxic agents: A comprehensive review

A Hosseini, BM Razavi, H Hosseinzadeh - Phytomedicine, 2023 - Elsevier
Background Different chemical toxicants or natural toxins can damage human health
through various routes such as air, water, fruits, foods, and vegetables. Purpose Herbal …

Ellagic acid protects against non-alcoholic fatty liver disease in streptozotocin-diabetic rats by activating AMPK

JZ ALTamimi, GM Alshammari, NA AlFaris… - Pharmaceutical …, 2022 - Taylor & Francis
Context Ellagic acid (EA) is used in traditional medicine to treated hyperlipidaemia.
Objective This study examined if AMPK mediates the anti-steatotic effect of ellagic acid (EA) …

[HTML][HTML] Ellagic acid attenuates arsenic induced neuro-inflammation and mitochondrial dysfunction associated apoptosis

F Firdaus, MF Zafeer, E Anis, M Ahmad, M Afzal - Toxicology reports, 2018 - Elsevier
Arsenic, being a global pollutant needs a potential remedy which could fight against its
associated toxicities. Ellagic acid (EA) is a known agent for its anti-inflammatory, antioxidant …

Ellagic acid in suppressing in vivo and in vitro oxidative stresses

A Zeb - Molecular and Cellular Biochemistry, 2018 - Springer
Oxidative stress is a biological condition produced by a variety of factors, causing several
chronic diseases. Oxidative stress was, therefore, treated with natural antioxidants, such as …

Ellagic acid in strawberry (Fragaria spp.): Biological, technological, stability, and human health aspects

S Muthukumaran, C Tranchant, J Shi… - Food Quality and …, 2017 - academic.oup.com
Ellagic acid (EA) is one of the plant phenolics associated with human health benefits. It
derives from ellagitannins found in some nuts, seeds, and fruits, especially berries …

Cyclophosphamide induced oxidative stress, lipid per oxidation, apoptosis and histopathological changes in rats: Protective role of boron

M Cengiz, V Sahinturk, SC Yildiz, İK Şahin… - Journal of Trace …, 2020 - Elsevier
Background Cyclophosphamide (CP) is an alkylating chemotherapeutic drug used in the
treatment of many types of cancer. However, as with other chemotherapeutic drugs, the use …

Ellagic acid prevents kidney injury and oxidative damage via regulation of Nrf-2/NF-κB signaling in carbon tetrachloride induced rats

A Aslan, O Gok, S Beyaz, CA Ağca, O Erman… - Molecular biology …, 2020 - Springer
Phytochemicals, bioactive food compounds, found in plants have been described as
protective agents against renal injury. This work was planned to evaluate the effects of EA …

[PDF][PDF] Ellagic acid protects against diabetic cardiomyopathy in rats by stimulating cardiac silent information regulator 1 signaling

JZ Altamimi, NA Alfaris, GM Alshammari… - J Physiol …, 2020 - researchgate.net
This study investigated the protective effect of ellagic acid (EA) against diabetic
cardiomyopathy (DC) in streptozotocin (STZ)-treated rats and examined if the mechanism of …

Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin–induced diabetic nephropathy in mice

WJ Yang, YR Li, H Gao, XY Wu, XL Wang… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacology relevance Rhizome of Ligusticum chuanxiong
Hort.(Abbreviated as LC) is a frequently prescribed component in plenty of traditional …