Microbes broadly constitute several organisms like viruses, protozoa, bacteria, and fungi
present in our biosphere. Fast-paced environmental changes have influenced contact of …

Leishmaniases are considered among the most neglected yet dangerous parasitic diseases
worldwide. According to the recent WHO report (Weekly Epidemiological Record, Sep …

Background Leishmaniasis is a disease caused by the protozoan parasite, Leishmania. The
disease remains a global threat to public health requiring effective chemotherapy for control …

Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually with over 500,000 deaths. Among the NTDs, some of the …

Despite advancements in the areas of omics and chemoinformatics, potent novel
biotherapeutic molecules with new modes of actions are needed for leishmaniasis. The …

Leishmaniasis is a vector-borne protozoan disease caused by an intracellular parasite
which globally affects 350 million people. This infectious disease mainly affects …

Studies in rural communities are important to maintain popular knowledge between
generations, as well as to identify new species for pharmaceutical production. Thus, the …

New therapeutics are urgently needed to treat visceral leishmaniasis (VL). Due to the fact
that drug discovery is a long and expensive process, the development of delivery systems to …

The development of new therapeutic strategies to treat leishmaniasis has become a priority.
In the present study, the antileishmanial activity of 8-hydroxyquinoline (8-HQN) was …

Amphotericin B (Amp) has been well-successfully used to treat against Leishmania infection,
although high toxicity has been found in patients. In the present study, Amp was …