Preexisting risk-avoidance and enhanced alcohol relief are driven by imbalance of the striatal dopamine receptors in mice

ME Bocarsly, MJ Shaw, E Ventriglia… - Nature …, 2024 - nature.com
Alcohol use disorder (AUD) is frequently comorbid with anxiety disorders, yet whether
alcohol abuse precedes or follows the expression of anxiety remains unclear. Rodents offer …

Anterior and Posterior Basolateral Amygdala Projections of Cell Type–Specific D1-Expressing Neurons From the Medial Prefrontal Cortex Differentially Control …

Z Li, J Li, Y Wei, W Zou, OE Vidjro, J Wang, L Zhou… - Biological …, 2024 - Elsevier
Background Alcohol use disorder is characterized by compulsive alcohol-seeking behavior,
which is associated with dysregulation of afferent projections from the medial prefrontal …

Behavioral changes and transcriptional regulation of mesolimbic dopaminergic genes in a mouse model of binge eating disorder by diet intermittent access

REM Júnior, ASB Pedersen, RM Ferreira… - The Journal of …, 2025 - Elsevier
Abstract Binge Eating Disorder (BED) is among the most prevalent eating disorders
worldwide. It is characterized by recurrent episodes of excessive consumption of palatable …

Brain-Region-Specific Genes Form the Major Pathways Featuring Their Basic Functional Role: Their Implication in Animal Chronic Stress Model

V Babenko, O Redina, D Smagin, I Kovalenko… - International Journal of …, 2024 - mdpi.com
The analysis of RNA-Sec data from murine bulk tissue samples taken from five brain regions
associated with behavior and stress response was conducted. The focus was on the most …

Striatal cell-type-specific molecular signatures reveal therapeutic targets in a model of dystonia

KM Roman, AR Dinasarapu, S Cherian, X Fan… - bioRxiv, 2024 - biorxiv.org
Striatal dysfunction is implicated in many forms of dystonia, including idiopathic, inherited
and iatrogenic dystonias. The striatum is comprised largely of GABAergic spiny projection …

Role of the Prefrontal Cortex to Dorsomedial Striatum Projections in Compulsive Alcohol Drinking

M Bauer - 2023 - scholarworks.iupui.edu
Compulsive alcohol drinking is a defining feature of alcohol use disorder and is
characterized as drinking alcohol despite knowledge of negative consequences. This …