Liver cancer is the third leading cause of cancer death worldwide. Representing such a
dramatic impact on our lives, liver cancer is a significant public health concern. Sustainable …

Liver cancers cause a high rate of death worldwide and hepatocellular carcinoma (HCC) is
considered as the most common primary liver cancer. HCC remains a challenging disease …

MYC, a major oncogenic transcription factor, regulates target genes involved in various
pathways such as cell proliferation, metabolism and immune evasion, playing a critical role …

Simple Summary Aberrant Wnt/β-catenin signaling has been reported to play crucial role in
pathogenesis of hepatocellular carcinoma (HCC). In this review, we focus on the regulatory …

Silymarin is used as a hepatoprotective agent since ancient times which could be via its
potent anti-oxidant effect. However, the mode of silymarin for the hepatoprotective effect has …

Liver cancer (hepatocellular carcinoma [HCC]) is a fatal cancer worldwide and often is
detected at an advanced stage when treatment options are very limited. This drives the …

Liver cancer is the fifth most widespread in the world, with a high fatality rate and poor
prognosis. However, surgicalresction, thermal/radiofrequencyablation, chemo …

The liver exhibits the highest recovery rate from acute injuries. However, in chronic liver
disease, the long-term loss of hepatocytes often leads to adverse consequences such as …

Simple Summary Cancer stem cells (CSCs) are known to be highly resistant to conventional
therapeutic approaches, such as chemotherapeutic drugs and radiation. Therefore …

Intervertebral Disc (IVD) degeneration has been associated with a chronic inflammatory
response, but knowledge on the contribution of distinct IVD cells, namely CD44, to the …