Immune checkpoint inhibitors have significantly transformed the treatment paradigm for
metastatic renal cell carcinoma (RCC), offering prolonged overall survival and achieving …

DNA methylation is a fundamental mechanism of epigenetic control in cells and its
dysregulation is strongly implicated in cancer development. Cancers possess an extensively …

Castration-resistant prostate cancer (CRPC) is a heterogeneous disease associated with
phenotypic subtypes that drive therapy response and outcome differences. Histologic …

Breast cancer is one of the most diagnosed cancers worldwide. Precise diagnosis and
subtyping have important significance for targeted therapy and prognosis prediction of …

Purpose: Histologic transformation to small cell lung cancer (SCLC) is a mechanism of
treatment resistance in patients with advanced oncogene-driven lung adenocarcinoma …

Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor
survival and a heightened response to immune checkpoint inhibitors (ICIs). Two major …

The rapidly expanding field of circular RNA (circ-RNA) research has opened new avenues
in cancer diagnostics and treatment, highlighting the role of serum circRNAs as potential …

Simple Summary Circulating tumor DNA (ctDNA) is a non-invasive method of identifying and
monitoring genitourinary cancers, including prostate, bladder, and renal cell carcinoma, via …

The complex relationship between chromatin accessibility, transcriptional regulation, and
cancer transitions presents a daunting puzzle. Terekhanova et al. created a pan-cancer …

This review provides a comprehensive overview of the latest advancements in the clinical
utility of liquid biopsy, with a particular focus on epigenetic approaches aimed at overcoming …