Hypertension is a major risk factor for cardiovascular disease, and reduction of elevated
blood pressure significantly reduces the risk of cardiovascular events. Endothelial …

The recent discovery of an enzyme which can synthesize the free radical gas nitric oxide
(NO) from L-arginine has shed new light on a number of curious, and, at first glance …

Nitric oxide, synthesized from the semiessential amino acid l-arginine by nitric oxide
synthase, is a remarkable regulatory molecule and plays an important role in physiological …

The central control of cardiovascular function has been keenly studied for a number of
decades. Of particular interest are the homeostatic control mechanisms, such as the …

The identification of nitric oxide (NO) as a gaseous, nonconventional neurotransmitter in the
central nervous system has led to an explosion of studies aimed at learning about the roles …

The vascular endothelium plays a fundamental role in the basal and dynamic regulation of
the circulation. Thus, it has a crucial role in the pathogenesis of hypertension. A spectrum of …

Nitric oxide (NO) has received attention as a vagal nonadrenergic‐noncholinergic (NANC)
mediator of gastrointestinal relaxation. The dorsal vagal complex (DVC) is the primary …

Nitric oxide (NO) may mediate penile erection by inhibiting smooth muscle of the corpora
cavernosa, thereby allowing vasodilation of the corpora. In order to test the role of NO in the …

Evidence has accumulated indicating that the interaction between NO and the autonomic
nervous system plays an important role in cardiovascular regulation, not only in …

Nitric oxide (NO) is a gaseous neurotransmitter that may mediate a decrease in sympathetic
output to the periphery. This implication predicts that NO‐producing neurons in the brain are …