The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics

L Qian, X Lin, X Gao, RU Khan, JY Liao, S Du… - Chemical …, 2023 - ACS Publications
The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …

[HTML][HTML] Artificial intelligence in pharmaceutical technology and drug delivery design

LK Vora, AD Gholap, K Jetha, RRS Thakur, HK Solanki… - Pharmaceutics, 2023 - mdpi.com
Artificial intelligence (AI) has emerged as a powerful tool that harnesses anthropomorphic
knowledge and provides expedited solutions to complex challenges. Remarkable …

[HTML][HTML] Engineered exosomes for cancer theranostics: Next-generation tumor targeting

VP Chavda, VV Sugandhi, CV Pardeshi, RJ Patil… - Journal of Drug Delivery …, 2023 - Elsevier
Exosomes are multivesicular bodies of which the plasma membrane fuse to release the
caring moiety into the surrounding body fluids. They are best known for their function in …

[HTML][HTML] Current status of Cancer Nanotheranostics: Emerging strategies for cancer management

VP Chavda, A Khadela, Y Shah, H Postwala… - …, 2023 - ncbi.nlm.nih.gov
Cancer diagnosis and management have been a slow-evolving area in medical science.
Conventional therapies have by far proved to have various limitations. Also, the concept of …

The promising role of tumor-associated macrophages in the treatment of cancer

H Wang, X Wang, X Zhang, W Xu - Drug Resistance Updates, 2024 - Elsevier
Macrophages are important components of the immune system. Mature macrophages can
be recruited to tumor microenvironment that affect tumor cell proliferation, invasion and …

Emerging Applications of Nanobiosensors in Pathogen Detection in Water and Food

HM Valenzuela-Amaro, A Aguayo-Acosta… - Biosensors, 2023 - mdpi.com
Food and waterborne illnesses are still a major concern in health and food safety areas.
Every year, almost 0.42 million and 2.2 million deaths related to food and waterborne illness …

Phytoestrogens: Chemistry, potential health benefits, and their medicinal importance

VP Chavda, AZ Chaudhari, PC Balar… - Phytotherapy …, 2024 - Wiley Online Library
Phytoestrogens, also known as xenoestrogens, are secondary metabolites derived from
plants that have similar structures and biological effects as human estrogens. These …

A CD326 monoclonal antibody modified core cross-linked curcumin-polyphosphoester prodrug for targeted delivery and cancer treatment

H Li, M Zhang, J He, J Liu, X Sun, P Ni - Journal of Materials Chemistry …, 2023 - pubs.rsc.org
Stimuli-responsive cross-linked micelles (SCMs) are ideal nanocarriers for anti-cancer
drugs. Compared with non-cross-linked micelles, SCMs exhibit superior structural stability …

[PDF][PDF] Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design. Pharmaceutics 2023, 15, 1916

LK Vora, AD Gholap, K Jetha, RR Thakur, HK Solanki… - 2023 - digitalrosh.com
Artificial intelligence (AI) has emerged as a powerful tool that harnesses anthropomorphic
knowledge and provides expedited solutions to complex challenges. Remarkable …

Oral Vaccine Delivery: Current Status

PC Balar, VA Modh, SP Chauhan… - … ‐Based Fast Track …, 2024 - Wiley Online Library
Vaccines are preparations of dead or weakened pathogens, such as bacteria or viruses,
that, when administered, induce the formation of antibodies or cellular protection against the …