Enterocytes regulate gut maintenance and defence by secreting and responding to
inflammatory mediators and by modulating the intestinal epithelial permeability. In order to …

Mesoporous silicon particles hold great potential in improving the solubility of otherwise
poorly soluble drugs. To effectively translate this feature into the clinic, especially via oral or …

For therapies targeting diseases of the gastrointestinal tract, we and others envision
probiotic bacteria that synthesize and excrete biotherapeutics at disease sites. Toward this …

Interaction of nanoparticles with food matrix components may cause unpredictable health
complications. Using an improved Caco-2 cell-based in vitro (co-) culture model the …

A pool of selected lactic acid bacteria was used to ferment suspensions of rye flour. Two-
dimensional electrophoresis showed that 109 of the 129 ethanol-soluble rye polypeptides …

Abstract Background and Aim: In the present paper, the toxicity of prolamines derived from
three cereals with a different genome was investigated in human colon cancer Caco‐2/TC7 …

Objective: Gut barrier dysfunction and bacterial translocation occur in various disorders,
including intestinal obstruction. Overexpression of inducible nitric oxide synthase is …

Background Inflammatory bowel disease [IBD] is characterised by abnormal host-microbe
interactions. Proinflammatory cytokine IFNγ and a novel tumour necrosis factor [TNF] …

We generated “sentinel” bacteria that respond to the biomarker nitric oxide (NO) and
produce a homogeneous and strong fluorescent response. Our dual-plasmid system …

Okadaic acid (OA) and its analogues, dinophysistoxin 1 (DTX1) and dinophysistoxin 2
(DTX2), are lipophilic and heat-stable marine toxins produced by dinoflagellates, which can …