Filling the gaps on stroke research: Focus on inflammation and immunity

D Levard, I Buendia, A Lanquetin, M Glavan… - Brain, behavior, and …, 2021 - Elsevier
For the last two decades, researchers have placed hopes in a new era in which a
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …

Cell-based and pharmacological neurorestorative therapies for ischemic stroke

P Venkat, Y Shen, M Chopp, J Chen - Neuropharmacology, 2018 - Elsevier
Ischemic stroke remains one of most common causes of death and disability worldwide.
Stroke triggers a cascade of events leading to rapid neuronal damage and death …

Minocycline can reduce testicular apoptosis related to varicocele in male rats

M Shokoohi, A Khaki, A Roudi Rasht Abadi… - Andrologia, 2022 - Wiley Online Library
The current research aimed to assess the impacts of Minocycline on varicocele‐induced
regulation of apoptotic‐related genes and oxidative stress in the testis of adult Wistar rats …

[HTML][HTML] Minocycline treatment prevents depression and anxiety-like behaviors and promotes neuroprotection after experimental ischemic stroke

QM Camargos, BC Silva, DG Silva… - Brain research …, 2020 - Elsevier
Depression and anxiety have been reported as the major neuropsychiatric consequences
following stroke. Minocycline, a neuroprotective drug has minimized depressive symptoms …

[HTML][HTML] Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review

Y Naderi, Y Panahi, GE Barreto… - Neural regeneration …, 2020 - journals.lww.com
To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal
models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and …

Attenuating effect of α-pinene on neurobehavioural deficit, oxidative damage and inflammatory response following focal ischaemic stroke in rat

M Khoshnazar, MR Bigdeli, S Parvardeh… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Oxidative stress and inflammation have a critical role in the pathogenesis of
ischaemic stroke. Alpha-pinene is a monoterpenoid molecule with anti-inflammatory and …

[HTML][HTML] Adenosine A2A receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-induced …

IG Ko, JJ Jin, L Hwang, SH Kim, CJ Kim, JW Jeon… - PLoS …, 2021 - journals.plos.org
Cerebral ischemia causes tissue death owing to occlusion of the cerebral blood vessels,
and cerebral ischemia activates mitogen-activated protein kinase (MAPK) and induces …

[HTML][HTML] Protective effect of minocycline on Bax and Bcl-2 gene expression, histological damages and oxidative stress induced by ovarian torsion in adult rats

MK Roshanaee, SH Abtahi-Eivary… - … Journal of Fertility & …, 2022 - ncbi.nlm.nih.gov
Background Minocycline is a widely used bacteriostatic antibiotic with various functions. The
aim of this study was to investigate impact of apoptotic genes in ovary of the …

Stanniocalcin-1 ameliorates cerebral ischemia by decrease oxidative stress and blood brain barrier permeability

S Bonfante, A Della Giustina, LG Danielski… - Microvascular …, 2020 - Elsevier
Blood brain barrier (BBB) permeability and oxidative stress have been reported to be
important mechanisms for brain damage following ischemic stroke and stanniocalcin-1 (STC …

Hyperoxia by short-term promotes oxidative damage and mitochondrial dysfunction in rat brain

RS Machado, L Tenfen, L Joaquim… - Respiratory Physiology …, 2022 - Elsevier
Oxygen (O 2) therapy is used as a therapeutic protocol to prevent or treat hypoxia. However,
a high inspired fraction of O 2 (FIO 2) promotes hyperoxia, a harmful condition for the central …