COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics
The novel coronavirus infection (COVID-19 or Coronavirus disease 2019) that emerged from
Wuhan, Hubei province of China has spread to many countries worldwide. Efforts have been …
Wuhan, Hubei province of China has spread to many countries worldwide. Efforts have been …
Lessons for COVID-19 immunity from other coronavirus infections
A Sariol, S Perlman - Immunity, 2020 - cell.com
A key goal to controlling coronavirus disease 2019 (COVID-19) is developing an effective
vaccine. Development of a vaccine requires knowledge of what constitutes a protective …
vaccine. Development of a vaccine requires knowledge of what constitutes a protective …
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
TP Sheahan, AC Sims, SR Leist, A Schäfer… - Nature …, 2020 - nature.com
Middle East respiratory syndrome coronavirus (MERS-CoV) is the causative agent of a
severe respiratory disease associated with more than 2468 human infections and over 851 …
severe respiratory disease associated with more than 2468 human infections and over 851 …
From SARS to MERS, thrusting coronaviruses into the spotlight
Z Song, Y Xu, L Bao, L Zhang, P Yu, Y Qu, H Zhu… - viruses, 2019 - mdpi.com
Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …
Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
E De Wit, F Feldmann, J Cronin… - Proceedings of the …, 2020 - National Acad Sciences
The continued emergence of Middle East Respiratory Syndrome (MERS) cases with a high
case fatality rate stresses the need for the availability of effective antiviral treatments …
case fatality rate stresses the need for the availability of effective antiviral treatments …
Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology
R Channappanavar, S Perlman - Seminars in immunopathology, 2017 - Springer
Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic
coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild …
coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild …
Coronavirus disease 2019–COVID-19
In recent decades, several new diseases have emerged in different geographical areas, with
pathogens including Ebola virus, Zika virus, Nipah virus, and coronaviruses (CoVs) …
pathogens including Ebola virus, Zika virus, Nipah virus, and coronaviruses (CoVs) …
Animal and translational models of SARS-CoV-2 infection and COVID-19
COVID-19 is causing a major once-in-a-century global pandemic. The scientific and clinical
community is in a race to define and develop effective preventions and treatments. The …
community is in a race to define and develop effective preventions and treatments. The …
Coronaviruses—drug discovery and therapeutic options
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
Virus infection induced pulmonary fibrosis
WJ Huang, XX Tang - Journal of translational medicine, 2021 - Springer
Pulmonary fibrosis is the end stage of a broad range of heterogeneous interstitial lung
diseases and more than 200 factors contribute to it. In recent years, the relationship between …
diseases and more than 200 factors contribute to it. In recent years, the relationship between …