On the simulation of mitral valve function in health, disease, and treatment
The mitral valve (MV) is the left atrioventricular heart valve that regulates blood flow between
the left atrium and left ventricle (LV) during the cardiac cycle. Contrary to the aortic valve …
the left atrium and left ventricle (LV) during the cardiac cycle. Contrary to the aortic valve …
A survey of modeling and optimization methods for multi-scale heterogeneous lattice structures
This paper aims to provide a comprehensive review of the state-of-the-art modeling and
optimization methods for multi-scale heterogeneous lattice structures (MSHLS) to further …
optimization methods for multi-scale heterogeneous lattice structures (MSHLS) to further …
A noninvasive method for the determination of in vivo mitral valve leaflet strains
Assessment of mitral valve (MV) function is important in many diagnostic, prognostic, and
surgical planning applications for treatment of MV disease. Yet, to date, there are no …
surgical planning applications for treatment of MV disease. Yet, to date, there are no …
Challenges and opportunities in geometric modeling of complex bio-inspired three-dimensional objects designed for additive manufacturing
N Letov, PT Velivela, S Sun… - Journal of …, 2021 - asmedigitalcollection.asme.org
Ever since its introduction over five decades ago, geometric solid modeling has been crucial
for engineering design purposes and is used in engineering software packages such as …
for engineering design purposes and is used in engineering software packages such as …
Pre-surgical Prediction of Ischemic Mitral Regurgitation Recurrence Using In Vivo Mitral Valve Leaflet Strains
Ischemic mitral regurgitation (IMR) is a prevalent cardiac disease associated with substantial
morbidity and mortality. Contemporary surgical treatments continue to have limited long-term …
morbidity and mortality. Contemporary surgical treatments continue to have limited long-term …
Development of a functionally equivalent model of the mitral valve chordae tendineae through topology optimization
Ischemic mitral regurgitation (IMR) is a currently prevalent disease in the US that is projected
to become increasingly common as the aging population grows. In recent years, image …
to become increasingly common as the aging population grows. In recent years, image …
In vivo assessment of mitral valve leaflet remodelling following myocardial infarction
Abstract Each year, more than 40,000 people undergo mitral valve (MV) repair surgery
domestically to treat regurgitation caused by myocardial infarction (MI). Although continual …
domestically to treat regurgitation caused by myocardial infarction (MI). Although continual …
Mitral valve leaflet response to ischaemic mitral regurgitation: from gene expression to tissue remodelling
DP Howsmon, BV Rego… - Journal of the …, 2020 - royalsocietypublishing.org
Ischaemic mitral regurgitation (IMR), a frequent complication following myocardial infarction
(MI), leads to higher mortality and poor clinical prognosis if untreated. Accumulating …
(MI), leads to higher mortality and poor clinical prognosis if untreated. Accumulating …
A Computational Pipeline for Patient-Specific Prediction of the Post-operative Mitral Valve Functional State
Mitral valve (MV) repair is safer than replacement for mitral regurgitation (MR) treatment, but
long-term outcomes remain suboptimal and poorly understood. Moreover, preoperative …
long-term outcomes remain suboptimal and poorly understood. Moreover, preoperative …
The three-dimensional microenvironment of the mitral valve: insights into the effects of physiological loads
Introduction In the mitral valve (MV), numerous pathological factors, especially those
resulting from changes in external loading, have been shown to affect MV structure and …
resulting from changes in external loading, have been shown to affect MV structure and …