The scientific effort to control the interaction between light and matter has grown
exponentially in the last 2 decades. This growth has been aided by the development of …

Ciliopathies are inherited human disorders caused by both motile and non‐motile cilia
dysfunction that form an important and rapidly expanding disease category. Ciliopathies are …

Immotile cilia at the ventral node of mouse embryos are required for sensing leftward fluid
flow that breaks left-right symmetry of the body. However, the flow-sensing mechanism has …

Cellular mechanisms underlying the development of left–right asymmetry in tissues and
embryos remain obscure. Here, the development of a chiral pattern of actomyosin was …

Cells have an intrinsic ability to self-assemble and self-organize into complex and functional
tissues and organs. By taking advantage of this ability, embryoids, organoids and …

Only a limited number of animal species lend themselves to becoming model organisms in
multiple biological disciplines: one of these is the great pond snail, Lymnaea stagnalis …

The function of normal and defective candidate genes for human genetic diseases, which
are rapidly being identified in large numbers by human geneticists and the biomedical …

The emergence of asymmetry from an initially symmetrical state is a universal transition in
nature. Living organisms show asymmetries at the molecular, cellular, tissular, and …

TGF-β family ligands function in inducing and patterning many tissues of the early vertebrate
embryonic body plan. Nodal signaling is essential for the specification of mesendodermal …

Vertebrates exhibit striking left–right (L–R) asymmetries in the structure and position of the
internal organs. Symmetry is broken by motile cilia-generated asymmetric fluid flow …