Evaluation and management of laryngopharyngeal reflux disease: state of the art review

JR Lechien, LM Akst, AL Hamdan… - … –Head and Neck …, 2019 - journals.sagepub.com
Objective To review the current literature about the epidemiology, clinical presentation,
diagnosis, and treatment of laryngopharyngeal reflux (LPR). Data Sources PubMed …

Normative ambulatory reflux monitoring metrics for laryngopharyngeal reflux: a systematic review of 720 healthy individuals

JR Lechien, WW Chan, LM Akst… - … –Head and Neck …, 2022 - journals.sagepub.com
Objectives To review the normative data for acid, weakly acid, and nonacid proximal
esophageal (PRE) and hypopharyngeal reflux (HRE) events in diagnosing …

Extraesophageal symptoms and diseases attributed to GERD: where is the pendulum swinging now?

MF Vaezi, D Katzka, F Zerbib - Clinical Gastroenterology and Hepatology, 2018 - Elsevier
The purpose of this review is to outline the recent developments in the field of
extraesophageal reflux disease and provide clinically relevant recommendations. The …

[HTML][HTML] Clinical update findings about pH-impedance monitoring features in laryngopharyngeal reflux patients

JR Lechien - Journal of Clinical Medicine, 2022 - mdpi.com
Purpose: The diagnosis of laryngopharyngeal reflux (LPR) is commonly based on non-
specific symptoms and findings and a positive response to an empirical therapeutic trial. The …

Correlation of salivary and nasal lavage pepsin with MII‐pH testing

MJ Klimara, N Johnston, TL Samuels… - The …, 2020 - Wiley Online Library
Objectives Laryngopharyngeal reflux (LPR) is a common upper airway disease. Salivary
pepsin is a proposed marker for LPR; however, the optimal time for collection of specimens …

[HTML][HTML] The human laryngeal microbiome: effects of cigarette smoke and reflux

ME Jetté, KA Dill-McFarland, AS Hanshew, G Suen… - Scientific reports, 2016 - nature.com
Prolonged diffuse laryngeal inflammation from smoking and/or reflux is commonly
diagnosed as chronic laryngitis and treated empirically with expensive drugs that have not …

[HTML][HTML] Diagnosis of Laryngopharyngeal Reflux: Past, Present, and Future—A Mini-Review

HC Lien, PH Lee, CC Wang - Diagnostics, 2023 - mdpi.com
Laryngopharyngeal reflux (LPR) is a variant of gastroesophageal reflux disease (GERD) in
which gastric refluxate irritates the lining of the aerodigestive tract and causes troublesome …

Association between laryngeal pepsin levels and the presence of vocal fold polyps

L Wang, JJ Tan, T Wu, R Zhang… - … –Head and Neck …, 2017 - journals.sagepub.com
Objective To determine whether pepsin, the main component of refluxed gastric contents, is
significantly associated with vocal fold polyps and to evaluate the diagnostic value of pepsin …

The edematous and erythematous airway does not denote pathologic gastroesophageal reflux

R Rosen, PD Mitchell, J Amirault, M Amin… - The Journal of …, 2017 - Elsevier
Objective To determine if the reflux finding score (RFS), a validated score for airway
inflammation, correlates with gastroesophageal reflux measured by multichannel …

Do laryngoscopic findings reflect the characteristics of reflux in patients with laryngopharyngeal reflux?

YC Lee, OE Kwon, JM Park, YG Eun - Clinical Otolaryngology, 2018 - Wiley Online Library
Objective To analyse the association between 24‐hour multichannel intraluminal
impedance‐pH (24‐h MII‐pH) parameters and each item of the reflux finding score (RFS) to …