Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble
proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly …

During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Many birds and mammals drastically reduce their energy expenditure during times of cold
exposure, food shortage, or drought, by temporarily abandoning euthermia, ie the …

The advent of endothermy, which is achieved through the continuous homeostatic regulation
of body temperature and metabolism,, is a defining feature of mammalian and avian …

Brown adipose tissue (BAT) burns fat to produce heat when the body is exposed to cold and
plays a role in energy metabolism. Using fluorodeoxyglucose-positron emission tomography …

Host defenses against pathogens are energetically expensive, leading ecological
immunologists to postulate that they might participate in energetic trade-offs with other …

Torpor is an energy-conserving state in which animals dramatically decrease their metabolic
rate and body temperature to survive harsh environmental conditions. Here, we report the …

The fertility and survival of an individual rely on the ability of the periphery to promptly,
effectively, and reproducibly communicate with brain neural networks that control …

The Mouse Metabolic Phenotyping Center (MMPC) Consortium was established to address
the need to characterize the growing number of mouse models of metabolic diseases …

All animals face the possibility of limitations in food resources that could ultimately lead to
starvation-induced mortality. The primary goal of this review is to characterize the various …