Nicotinamide adenine dinucleotide phosphate (NAPDH) oxidase (NOX) is an enzyme
complex with the sole function of producing superoxide anion and reactive oxygen species …

Hyperglycemia affects approximately one-third of acute ischemic stroke patients and is
associated with poor clinical outcomes. In experimental and clinical stroke studies …

Hyperglycolysis, observed within the penumbra zone during brain ischemia, was shown to
be detrimental for tissue survival because of lactate accumulation and reactive oxygen …

Objective The purpose of this study was to evaluate the antioxidant activity, phenolic and
flavonoids contents of selected medicinal plants form the Western region of Nepal. Methods …

Tripartite motif (TRIM) 31 has been implicated in diverse biological and pathological
conditions. However, whether TRIM31 plays a role in ischemic stroke progression is not …

Agomelatine is an agonist of the melatonergic MT1/MT2 receptors and an antagonist of the
serotonergic 5-HT receptors. Its actions mimic melatonin in antioxidative and anti …

Abstract Ischemia–reperfusion (I/R) injury induces the generation of reactive oxygen species
(ROS), which results in a poor prognosis for ischemic stroke patients. This study was …

The clinical manifestations that occur after traumatic brain injury (TBI) include a wide range
of cognitive, emotional, and behavioral deficits. The loss of excitatory synapses could …

In this paper, our review series on cerebrovascular disease anatomy, physiology, and
pathology ends with a thorough discussion of the most significant cerebrovascular …

We previously demonstrated that mice which overexpress human renin and
angiotensinogen (R+ A+) show enhanced cerebral damage in both in vivo and in vitro …