Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative
disease that affects the central nervous system (CNS). MS is characterized by immune …

During the past decade, accumulating evidence from the research highlights the suggested
effects of bacterial communities of the human gut microbiota and their metabolites on health …

Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents
may induce autoimmunity. It occurs when similarities between foreign and self-peptides …

Multiple sclerosis is an autoimmune disease that is caused by the interplay of genetic,
particularly the HLA-DR15 haplotype, and environmental risk factors. How these etiologic …

Multiple sclerosis (MS) is a debilitating autoimmune disorder. Currently, there is a lack of
effective treatment for the progressive form of MS, partly due to insensitive readout for …

We introduce an approach to identify disease-relevant tissues and cell types by analyzing
gene expression data together with genome-wide association study (GWAS) summary …

Multiple sclerosis (MS) is an immune-mediated disease, the etiology of which involves both
genetic and environmental factors. The exact nature of the environmental factors …

Whereas the study of the interactions between the immune system and the central nervous
system (CNS) has often focused on pathological conditions, the importance of neuroimmune …

Dietary interventions have not been effective in the treatment of multiple sclerosis (MS).
Here, we show that periodic 3-day cycles of a fasting mimicking diet (FMD) are effective in …

CD4+ T cells are crucial for directing appropriate immune responses during host defense
and for the pathogenesis of inflammatory diseases. In addition to the classical biphasic …