Diabetes mellitus has become a serious and chronic metabolic disorder that results from a
complex interaction of genetic and environmental factors, principally characterized by …

Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively
expanded in vitro. Although their true in situ properties and biological functions remain to be …

Mesenchymal stem/stromal cells (MSCs) are increasingly used as an intravenously applied
cellular therapeutic. They were found to be potent in situations such as tissue repair or …

Quantitative assays for human DNA and mRNA were used to examine the paradox that
intravenously (iv) infused human multipotent stromal cells (hMSCs) can enhance tissue …

The study of MSC trafficking is clinically relevant for minimally invasive cell therapy to
promote regeneration of damaged tissue, to treat inflammation, and to promote …

Background—Cardiac cell therapy for older patients who experience a myocardial infarction
may require highly regenerative cells from young, healthy (allogeneic) donors. Bone marrow …

Human mesenchymal stem cells (MSCs) communicate with other cells in the human body
and appear to “home” to areas of injury in response to signals of cellular damage, known as …

Traumatic brain injury (TBI) is a major cause of injury-related mortality and morbidity in the
USA and around the world. The survivors may suffer from cognitive and memory deficits …

Vascularization of engineered tissues in vitro and in vivo remains a key problem in
translation of engineered tissues to clinical practice. Growth factor signalling can be …

Stroke represents a severe medical condition that causes stroke survivors to suffer from long-
term and even lifelong disability. Over the past several decades, a vast majority of stroke …