Metals to combat antimicrobial resistance

A Frei, AD Verderosa, AG Elliott, J Zuegg… - Nature Reviews …, 2023 - nature.com
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

The microbiome-shaping roles of bacteriocins

S Heilbronner, B Krismer, H Brötz-Oesterhelt… - Nature Reviews …, 2021 - nature.com
The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

JE Choby, J Howard‐Anderson… - Journal of internal …, 2020 - Wiley Online Library
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global
pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing …

The Role of Macrophages in Staphylococcus aureus Infection

GR Pidwill, JF Gibson, J Cole, SA Renshaw… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is a member of the human commensal microflora that exists,
apparently benignly, at multiple sites on the host. However, as an opportunist pathogen it …

An Update on the Genus Aeromonas: Taxonomy, Epidemiology, and Pathogenicity

A Fernández-Bravo, MJ Figueras - Microorganisms, 2020 - mdpi.com
The genus Aeromonas belongs to the Aeromonadaceae family and comprises a group of
Gram-negative bacteria widely distributed in aquatic environments, with some species able …

Klebsiella pneumoniae infection biology: living to counteract host defences

JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

Virulence Factors in Hypervirulent Klebsiella pneumoniae

J Zhu, T Wang, L Chen, H Du - Frontiers in microbiology, 2021 - frontiersin.org
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the
Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae …

Iron homeostasis in plants–a brief overview

JM Connorton, J Balk, J Rodríguez-Celma - Metallomics, 2017 - academic.oup.com
Iron plays a crucial role in biochemistry and is an essential micronutrient for plants and
humans alike. Although plentiful in the Earth's crust it is not usually found in a form readily …

Role of bacterial efflux pumps in antibiotic resistance, virulence, and strategies to discover novel efflux pump inhibitors

A Gaurav, P Bakht, M Saini, S Pandey… - …, 2023 - microbiologyresearch.org
The problem of antibiotic resistance among pathogenic bacteria has reached a crisis level.
The treatment options against infections caused by multiple drug-resistant bacteria are …

Biosynthesis of fluopsin C, a copper-containing antibiotic from Pseudomonas aeruginosa

JB Patteson, AT Putz, L Tao, WC Simke, LH Bryant III… - Science, 2021 - science.org
Metal-binding natural products contribute to metal acquisition and bacterial virulence, but
their roles in metal stress response are underexplored. We show that a five-enzyme pathway …