Key molecules of fatty acid metabolism in gastric cancer

C Li, L Zhang, Z Qiu, W Deng, W Wang - Biomolecules, 2022 - mdpi.com
Fatty acid metabolism is closely linked to the progression of gastric cancer (GC), a very
aggressive and life-threatening tumor. This study examines linked molecules, such as Sterol …

Overview of cancer metabolism and signaling transduction

HS Chae, ST Hong - International Journal of Molecular Sciences, 2022 - mdpi.com
Despite the remarkable progress in cancer treatment up to now, we are still far from
conquering the disease. The most substantial change after the malignant transformation of …

Too complex to fail? Targeting fatty acid metabolism for cancer therapy

R Munir, J Lisec, JV Swinnen, N Zaidi - Progress in lipid research, 2022 - Elsevier
Given the central role of fatty acids in cancer pathophysiology, the exploitation of fatty acid
metabolism as a potential antineoplastic therapy has gained much attention. Several natural …

The role of mitochondrial fat oxidation in cancer cell proliferation and survival

MP De Oliveira, M Liesa - Cells, 2020 - mdpi.com
Tumors remodel their metabolism to support anabolic processes needed for replication, as
well as to survive nutrient scarcity and oxidative stress imposed by their changing …

Development of an efficient on-tissue epoxidation reaction mediated by urea hydrogen peroxide for MALDI MS/MS imaging of lipid C═ C location isomers

R Sun, W Tang, P Li, B Li - Analytical Chemistry, 2023 - ACS Publications
Unsaturated lipids containing different numbers and locations of C═ C bonds are
significantly associated with a variety of cellular and metabolic functions. Although matrix …

Lipids and Lipid Metabolism in Cellular Senescence: Emerging Targets for Age-Related Diseases

Q Zeng, YZ Gong, N Zhu, YN Shi, CJ Zhang… - Ageing Research …, 2024 - Elsevier
Cellular senescence is a kind of cellular state triggered by endogenous or exogenous
stimuli, which is mainly characterized by stable cell cycle arrest and complex senescence …

To be or not to be a fat burner, that is the question for cpt1c in cancer cells

R Fadó, S Zagmutt, L Herrero, H Muley… - Cell Death & …, 2023 - nature.com
There is an urgent need to identify reliable genetic biomarkers for accurate diagnosis,
prognosis, and treatment of different tumor types. Described as a prognostic marker for many …

[HTML][HTML] Targeting fatty acid uptake and metabolism in cancer cells: A promising strategy for cancer treatment

R Mallick, P Bhowmik, AK Duttaroy - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Despite scientific development, cancer is still a fatal disease. The development of cancer is
thought to be significantly influenced by fatty acids. Several mechanisms that control fatty …

[HTML][HTML] Interactions between oxidative stress and senescence in cancer: Mechanisms, therapeutic implications, and future perspectives

D Li, Q Yu, R Wu, Z Tuo, J Wang, L Ye, F Shao… - Redox Biology, 2024 - Elsevier
Background Recently, numerous studies have reported the interaction between senescence
and oxidative stress in cancer. However, there is a lack of a comprehensive understanding …

[HTML][HTML] The relevance of organelle interactions in cellular senescence

J Huang, P Meng, C Wang, Y Zhang, L Zhou - Theranostics, 2022 - ncbi.nlm.nih.gov
Organelles are tiny structures with specific functions in eukaryotic cells. Since they are
covered with membranes, different organelles can perform biological processes that are …