Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Polycystic ovary syndrome (PCOS) is a heterogeneous and complex disorder that has both
adverse reproductive and metabolic implications for affected women. However, there is …

III. IGFs and Their Receptors A. IGF peptides and receptors B. Expression of IGFs and IGF
receptors in the ovary C. Role of IGFs in ovulatory function and steroidogenesis

Abstract Approximately 20–30% of PCOS women demonstrate excess adrenal precursor
androgen (APA) production, primarily using DHEAS as a marker of APA in general and more …

Pronounced adrenarche with precocious pubarche (PP) in girls has been associated with
hyperinsulinism and subsequent functional ovarian hyperandrogenism (FOH). Recently …

Adrenarche is the puberty of the adrenal gland. The descriptive term pubarche indicates the
appearance of pubic hair, which may be accompanied by axillary hair. This process is …

Early pubertal maturation has been identified as a potential risk factor for internalizing and
externalizing problems during adolescence. However, questions about the mechanisms that …

Context: Polycystic ovary syndrome (PCOS) appears to arise as a complex trait with
contributions from both heritable and nonheritable factors. Polygenic influences appear to …

Context: A significant proportion of the first-degree female relatives of women with polycystic
ovary syndrome (PCOS) may be at risk for developing PCOS. However, it is not known at …

BACKGROUND The functional reproductive alterations seen in women with type 1 diabetes
(T1D) have changed as therapy has improved. Historically, patients with T1D and insufficient …