Diabetes mellitus comprises a group of carbohydrate metabolism disorders that share a
common main feature of chronic hyperglycemia that results from defects of insulin secretion …

Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …

The incidence of diabetes and its associated micro-and macrovascular complications is
greatly increasing worldwide. The most prevalent vascular complications of both type 1 and …

The most common and increasing causes of death worldwide are cardiovascular diseases
(CVD). Taking into account the fact that diet is a key factor, it is worth exploring this aspect of …

Diabetic nephropathy (DN), a severe microvascular complication frequently associated with
both type 1 and type 2 diabetes mellitus, is a leading cause of renal failure. The condition …

Living organisms and individual cells continuously adapt to changes in their environment.
Those changes are particularly sensitive to fluctuations in the availability of energy …

Type 2 diabetes mellitus (DM) is a common metabolic disorder predisposing to diabetic
cardiomyopathy and atherosclerotic cardiovascular disease (CVD), which could lead to …

In addition to genetic predisposition, environmental and lifestyle factors contribute to the
pathogenesis of type 2 diabetes (T2D). Epigenetic changes may provide the link for …

We examined whether persistence of epigenetic DNA methylation (DNA-me) alterations at
specific loci over two different time points in people with diabetes are associated with …