The therapeutic journey of benzimidazoles: A review

Y Bansal, O Silakari - Bioorganic & medicinal chemistry, 2012 - Elsevier
Presence of benzimidazole nucleus in numerous categories of therapeutic agents such as
antimicrobials, antivirals, antiparasites, anticancer, anti-inflammatory, antioxidants, proton …

Second and third-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumour activity

GV Suárez-Moreno, D Hernández-Romero… - Coordination Chemistry …, 2022 - Elsevier
The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …

[HTML][HTML] Synthesis and characterization of different complexes derived from Schiff base and evaluation as a potential anticancer, antimicrobial, and insecticide agent

LM Aroua, SK Alhag, LA Al-Shuraym… - Saudi Journal of …, 2023 - Elsevier
The condensation of (1H-benzimidazole-2-yl) methanamine, with 2-hydroxy
naphthaldehyde lead to Schiff base ligand (H2L)(1). This was later reacted with metal salts …

Structure− activity relationship of new anti-Hepatitis C virus agents: Heterobicycle− coumarin conjugates

J Neyts, ED Clercq, R Singha, YH Chang… - Journal of medicinal …, 2009 - ACS Publications
For establishment of the structure− activity relationship, 19 heterobicycle-coumarin
conjugated compounds with the− SCH2− linker were synthesized and found to possess …

Synthesis and characterization of dinuclear macrocyclic cobalt (II), copper (II) and zinc (II) complexes derived from 2, 2, 2′, 2′-S, S [bis (bis-N, N-2 …

F Arjmand, M Aziz - European journal of medicinal chemistry, 2009 - Elsevier
New homodinuclear macrocyclic complexes of cobalt (II), copper (II) and zinc (II) were
isolated from the newly synthesized ligand 2, 2, 2′, 2′-S, S [bis (bis-N, N-2 …

Synthesis of new conjugated coumarin–benzimidazole hybrids and their anticancer activity

K Paul, S Bindal, V Luxami - Bioorganic & medicinal chemistry letters, 2013 - Elsevier
A series of novel coumarin–benzimidazole hybrids, 3-(1H-benzo [d] imidazol-2-yl)-7-
(substituted amino)-2H-chromen-2-one derivatives of biological interest were synthesized …

[HTML][HTML] Synthesis, spectral characterization, antimicrobial evaluation studies and cytotoxic activity of some transition metal complexes with tridentate (N, N, O) donor …

HAK Kyhoiesh, KJ Al-Adilee - Results in Chemistry, 2021 - Elsevier
A new azo dye ligand 2-[2'-(6-methoxybenzothiazolyl) azo]-4-ethoxyphenol (6-MBTAEP)
was prepared by reacting a diazonium chloride salt solution of 2-amino-6-methoxy …

New transition metal ion complexes with benzimidazole-5-carboxylic acid hydrazides with antitumor activity

SA Galal, KH Hegab, AS Kassab, ML Rodriguez… - European journal of …, 2009 - Elsevier
Metal complexes of 2-methyl-1H-benzimidazole-5-carboxylic acid hydrazide (4a; L1) and its
Schiff base 2-methyl-N-(propan-2-ylidene)-1H-benzimidazole-5-carbohydrazide (5a; L2) …

Medical implications of benzimidazole derivatives as drugs designed for targeting DNA and DNA associated processes

S Bhattacharya, P Chaudhuri - Current medicinal chemistry, 2008 - ingentaconnect.com
Properties of benzimidazole and its derivatives have been studied for over hundred years;
special interest of researchers triggered by the fact that 5, 6-dimethylbenzimidazole is a …

Synthesis, characterization, antiamoebic activity and cytotoxicity of novel series of pyrazoline derivatives bearing quinoline tail

F Hayat, A Salahuddin, S Umar, A Azam - European journal of medicinal …, 2010 - Elsevier
The cyclization of chalcones (1a–1j) with 2-(quinolin-8-yloxy) acetohydrazide (2) under
basic condition led to the formation of new compounds, pyrazoline derivatives (3a–3j). In …