Wound healing: from passive to smart dressings

M Farahani, A Shafiee - Advanced Healthcare Materials, 2021 - Wiley Online Library
The universal increase in the number of patients with nonhealing skin wounds imposes a
huge social and economic burden on the patients and healthcare systems. Although, the …

New technologies for analysis of extracellular vesicles

H Shao, H Im, CM Castro, X Breakefield… - Chemical …, 2018 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

Extracellular vesicles derived from mesenchymal stem cells (MSC) in regenerative medicine: applications in skin wound healing

A Casado-Díaz, JM Quesada-Gómez… - … in Bioengineering and …, 2020 - frontiersin.org
The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …

The potential use of mesenchymal stem cells and their exosomes in Parkinson's disease treatment

RM Heris, M Shirvaliloo, S Abbaspour-Aghdam… - Stem Cell Research & …, 2022 - Springer
Parkinson's disease (PD) is the second most predominant neurodegenerative disease
worldwide. It is recognized clinically by severe complications in motor function caused by …

Stem cell-derived exosomes: a new strategy of neurodegenerative disease treatment

N Fayazi, M Sheykhhasan, S Soleimani Asl… - Molecular …, 2021 - Springer
Short-term symptomatic treatment and dose-dependent side effects of pharmacological
treatment for neurodegenerative diseases have forced the medical community to seek an …

Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy

KS Park, K Svennerholm, R Crescitelli… - Journal of …, 2021 - Wiley Online Library
Bacterial outer membrane vesicles (OMV) have gained attention as a promising new cancer
vaccine platform for efficiently provoking immune responses. However, OMV induce severe …

Subpopulations of extracellular vesicles and their therapeutic potential

C Lässer, SC Jang, J Lötvall - Molecular aspects of medicine, 2018 - Elsevier
Extracellular vesicles (EVs), such as exosomes and microvesicles, have over the last 10–15
years been recognized to convey key messages in the molecular communication between …

Mesenchymal stromal cell-derived nanovesicles ameliorate bacterial outer membrane vesicle-induced sepsis via IL-10

KS Park, K Svennerholm, GV Shelke… - Stem cell research & …, 2019 - Springer
Background Sepsis remains a source of high mortality in hospitalized patients despite
proper antibiotic approaches. Encouragingly, mesenchymal stromal cells (MSCs) and their …

Osteoblast‐derived extracellular vesicles are biological tools for the delivery of active molecules to bone

A Cappariello, A Loftus, M Muraca… - Journal of Bone and …, 2018 - academic.oup.com
Extracellular vesicles (EVs) are newly appreciated regulators of tissue homeostasis and a
means of intercellular communication. Reports have investigated the role of EVs and their …

Extracellular vesicles from mesenchymal stem cells: towards novel therapeutic strategies for neurodegenerative diseases

E Turano, I Scambi, F Virla, B Bonetti… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases are fatal disorders of the central nervous system (CNS) which
currently lack effective treatments. The application of mesenchymal stem cells (MSCs) …