Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer

F Ye, S Dewanjee, Y Li, NK Jha, ZS Chen, A Kumar… - Molecular cancer, 2023 - Springer
Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …

The anti-cancer effect of quercetin: molecular implications in cancer metabolism

M Reyes-Farias, C Carrasco-Pozo - International journal of molecular …, 2019 - mdpi.com
Cancer is a problem with worldwide importance and is the second leading cause of death
globally. Cancer cells reprogram their metabolism to support their uncontrolled expansion …

Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update

M Mehta, DS Dhanjal, KR Paudel, B Singh… - …, 2020 - Springer
Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …

The interplay between androgens and the immune response in polycystic ovary syndrome

S Shabbir, E Khurram, VS Moorthi, YTH Eissa… - Journal of Translational …, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a metabolic-reproductive-endocrine disorder that,
while having a genetic component, is known to have a complex multifactorial etiology. As …

Targeting PI3K/AKT/mTOR signaling pathway in breast cancer

H Li, L Prever, E Hirsch, F Gulluni - Cancers, 2021 - mdpi.com
Simple Summary PI3K signaling pathway plays an essential role in many cellular processes
and is frequently altered in breast cancer, leading to increased tumor growth and reduced …

Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy

H Hua, Q Kong, J Yin, J Zhang, Y Jiang - Journal of hematology & …, 2020 - Springer
Insulin-like growth factors (IGFs) play important roles in mammalian growth, development,
aging, and diseases. Aberrant IGFs signaling may lead to malignant transformation and …

[HTML][HTML] Properties and behavior of carbon nanomaterials when interfacing neuronal cells: How far have we come?

R Rauti, M Musto, S Bosi, M Prato, L Ballerini - Carbon, 2019 - Elsevier
In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …

NSAIDs and cancer resolution: new paradigms beyond cyclooxygenase

OR Kolawole, K Kashfi - International journal of molecular sciences, 2022 - mdpi.com
Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

[HTML][HTML] Selenium and tellurium in the development of novel small molecules and nanoparticles as cancer multidrug resistance reversal agents

E Domínguez-Álvarez, B Rácz, MA Marć… - Drug Resistance …, 2022 - Elsevier
Selenium is an essential trace element that is crucial for cellular antioxidant defense against
reactive oxygen species (ROS). Recently, many selenium-containing compounds have …

SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant

H Guo, X Yu, Y Liu, DT Paik, JM Justesen… - Science translational …, 2023 - science.org
The common aldehyde dehydrogenase 2 (ALDH2) alcohol flushing variant known as
ALDH2* 2 affects∼ 8% of the world's population. Even in heterozygous carriers, this …