Amphiphilic small molecule antimicrobials: From cationic antimicrobial peptides (CAMPs) to mechanism-related, structurally-diverse antimicrobials
J Yuan, J Wang, X Li, Y Zhang, J Xian, C Wang… - European Journal of …, 2023 - Elsevier
Bacterial infections are characterized by their rapid and widespread proliferation, leading to
significant morbidity. Despite the availability of a variety of antimicrobial drugs, the …
significant morbidity. Despite the availability of a variety of antimicrobial drugs, the …
Smart multifunctional polymer systems as alternatives or supplements of antibiotics to overcome bacterial resistance
In recent years, infectious diseases have again become a critical threat to global public
health largely due to the challenges posed by antimicrobial resistance. Conventional …
health largely due to the challenges posed by antimicrobial resistance. Conventional …
Facial amphiphilic naphthoic acid-derived antimicrobial polymers against multi-drug resistant gram-negative bacteria and biofilms
Inspired by the facial amphiphilic nature and antimicrobial efficacy of many antimicrobial
peptides, this work reported facial amphiphilic bicyclic naphthoic acid derivatives with …
peptides, this work reported facial amphiphilic bicyclic naphthoic acid derivatives with …
An optimized analog of antimicrobial peptide Jelleine-1 shows enhanced antimicrobial activity against multidrug resistant P. aeruginosa and negligible toxicity in vitro …
J Zhou, L Zhang, Y He, K Liu, F Zhang, H Zhang… - European Journal of …, 2021 - Elsevier
Due to the threat of escalating multi-drug resistant gram-negative bacteria to human health
and life, novel antimicrobial agents against gram-negative pathogens are urgently needed …
and life, novel antimicrobial agents against gram-negative pathogens are urgently needed …
Unlocking the bacterial membrane as a therapeutic target for next-generation antimicrobial amphiphiles
Gram-positive bacteria like Enterococcus faecium and Staphylococcus aureus, and Gram-
negative bacteria like Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …
negative bacteria like Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …
Recent developments in membrane targeting antifungal agents to mitigate antifungal resistance
Fungal infections cause severe and life-threatening complications especially in
immunocompromised individuals. Antifungals targeting cellular machinery and cell …
immunocompromised individuals. Antifungals targeting cellular machinery and cell …
Cholic acid-peptide conjugates as potent antimicrobials against interkingdom polymicrobial biofilms
Interkingdom polymicrobial biofilms formed by Gram-positive Staphylococcus aureus and
Candida albicans pose serious threats of chronic systemic infections due to the absence of …
Candida albicans pose serious threats of chronic systemic infections due to the absence of …
Microbial interkingdom biofilms and the quest for novel therapeutic strategies
K Van Dyck, RM Pinto, D Pully, P Van Dijck - Microorganisms, 2021 - mdpi.com
Fungal and bacterial species interact with each other within polymicrobial biofilm
communities in various niches of the human body. Interactions between these species can …
communities in various niches of the human body. Interactions between these species can …
Cleavable Amphiphilic Biocides with Ester-Bearing Moieties: Aggregation Properties and Antibacterial Activity
The rise of multidrug-resistant bacterial infections and the dwindling supply of newly
approved antibiotics have emerged as a grave threat to public health. Toward the ever …
approved antibiotics have emerged as a grave threat to public health. Toward the ever …
Recent advances in steroid amino acid conjugates: Old scaffolds with new dimensions
P Singla, DB Salunke - European Journal of Medicinal Chemistry, 2020 - Elsevier
Hybrid chemical compounds formed by conjugation of two or more bioactive molecules have
shown wide variety of applications in biology, microelectronics as well as material sciences …
shown wide variety of applications in biology, microelectronics as well as material sciences …