Platelets have a crucial role in haemostasis and atherothrombosis. Pharmacological control
of platelet hyper-reactivity has become a cornerstone in the prevention of thrombo …

Objective To evaluate the efficacy and safety of standard term (12 months) or long term (> 12
months) dual antiplatelet therapy (DAPT) versus short term (< 6 months) DAPT after …

Importance Data on P2Y12 inhibitor monotherapy after short-duration dual antiplatelet
therapy (DAPT) in patients undergoing percutaneous coronary intervention are limited …

Background The optimal technique of percutaneous coronary intervention in patients at high
bleeding risk is not known. The hypothesis of the DEBUT trial was that percutaneous …

Objectives The aim of this study was to evaluate the hypothesis that prasugrel monotherapy
following successful everolimus-eluting stent implantation is feasible and safe in patients …

Background: Patients at high-bleeding risk (HBR) undergoing percutaneous coronary
intervention represent a challenging patient population. The use of drug-coated balloon …

Background Bleeding is the principal safety concern of antithrombotic therapy and occurs
frequently among patients with coronary artery disease (CAD). Aims We aimed to evaluate …

Background The long-term prognostic impact of post-discharge bleeding in the unique
population of patients with acute coronary syndrome (ACS) treated without percutaneous …

Objectives The study sought to evaluate the impact of diabetes mellitus on 3-year clinical
outcome in patients undergoing drug-coated balloon (DCB) or drug-eluting stent (DES) …

Background After a brief period of dual antiplatelet therapy, P2Y12 inhibitor monotherapy in
the absence of aspirin effectively reduces bleeding without increasing recurrent ischemia in …