Porcine reproductive and respiratory syndrome virus (PRRSV): pathogenesis and interaction with the immune system

JK Lunney, Y Fang, A Ladinig, N Chen… - Annual review of …, 2016 - annualreviews.org
This review addresses important issues of porcine reproductive and respiratory syndrome
virus (PRRSV) infection, immunity, pathogenesis, and control. Worldwide, PRRS is the most …

Regulatory T cells in arterivirus and coronavirus infections: do they protect against disease or enhance it?

TE Cecere, SM Todd, T LeRoith - Viruses, 2012 - mdpi.com
Regulatory T cells (Tregs) are a subset of T cells that are responsible for maintaining
peripheral immune tolerance and homeostasis. The hallmark of Tregs is the expression of …

Evaluation of immune responses to porcine reproductive and respiratory syndrome virus in pigs during early stage of infection under farm conditions

V Dwivedi, C Manickam, B Binjawadagi, D Linhares… - Virology journal, 2012 - Springer
Background Porcine reproductive and respiratory syndrome virus (PRRSV) causes chronic,
economically devastating disease in pigs of all ages. Frequent mutations in the viral genome …

[HTML][HTML] Porcine reproductive and respiratory syndrome virus induces CD4+ CD8+ CD25+ Foxp3+ regulatory T cells (Tregs)

E Silva-Campa, V Mata-Haro, E Mateu, J Hernández - Virology, 2012 - Elsevier
The aim of this study was to analyze the regulatory T cells (Tregs) induced by the porcine
reproductive and respiratory syndrome virus (PRRSV) in pigs. Serum, blood, tonsil, and …

Adjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective …

B Binjawadagi, V Dwivedi, C Manickam… - International Journal …, 2014 - Taylor & Francis
Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus
(PRRSV), is an economically devastating disease, causing daily losses of approximately $3 …

Cross-protective immunity to porcine reproductive and respiratory syndrome virus by intranasal delivery of a live virus vaccine with a potent adjuvant

V Dwivedi, C Manickam, R Patterson, K Dodson… - Vaccine, 2011 - Elsevier
Porcine reproductive and respiratory syndrome (PRRS) is an immunosuppressive chronic
respiratory viral disease of pigs that is responsible for major economic losses to the swine …

Adjuvants for swine vaccines: Mechanisms of actions and adjuvant effects

W Charerntantanakul - Vaccine, 2020 - Elsevier
This review deals with mechanisms of actions (MOA) and adjuvant effects of various types of
adjuvants for swine vaccines. A number of different types of adjuvants have been tested with …

Gene expression of peripheral blood mononuclear cells and CD8+ T cells from gilts after PRRSV infection

E Lagumdzic, CPS Pernold, R Ertl, N Palmieri… - Frontiers in …, 2023 - frontiersin.org
Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive-stranded RNA
virus, which emerged in Europe and USA in the late 1980s and has since caused huge …

A single dose polyanhydride-based nanovaccine against paratuberculosis infection

A Thukral, K Ross, C Hansen, Y Phanse… - npj Vaccines, 2020 - nature.com
Mycobacterium avium subsp. paratuberculosis (M. paratuberculosis) causes Johne's
disease in ruminants and is characterized by chronic gastroenteritis leading to heavy …

The viral innate immune antagonism and an alternative vaccine design for PRRS virus

H Ke, D Yoo - Veterinary microbiology, 2017 - Elsevier
Porcine reproductive and respiratory syndrome (PRRS) remains one of the most
economically significant diseases in the swine industry worldwide. The current vaccines are …