Meta-analyses of genome-wide association studies (meta-GWASs) and candidate gene
studies have identified genetic variants associated with cardiovascular diseases, metabolic …

The solute carrier (SLC) superfamily comprises more than 400 transport proteins mediating
the influx and efflux of substances such as ions, nucleotides, and sugars across biological …

Summary The 1000 Genomes Project (1kGP) is the largest fully open resource of whole-
genome sequencing (WGS) data consented for public distribution without access or use …

摘要2 型糖尿病已经成为全球公共卫生的主要挑战. 迄今为止, 通过全基因组关联研究(genome‐
wide association studies, GWAS) 总共已经鉴定出了83 个2 型糖尿病易感位点. 为了发现2 …

To understand the genetics of type 2 diabetes in people of Japanese ancestry, we
conducted A meta-analysis of four genome-wide association studies (GWAS; 36,614 cases …

Importance Latino populations have one of the highest prevalences of type 2 diabetes
worldwide. Objectives To investigate the association between rare protein-coding genetic …

During the past 7 years, genome-wide association studies have shed light on the
contribution of common genomic variants to the genetic architecture of type 2 diabetes …

Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However,
little is known about the genetic risk in African Americans despite the recent identification of …

Genome-wide association studies (GWAS) have identified more than 80 susceptibility loci
for type 2 diabetes (T2D), but most of its heritability still remains to be elucidated. In this …

Summary Type 2 diabetes (T2D) affects Latinos at twice the rate seen in populations of
European descent. We recently identified a risk haplotype spanning SLC16A11 that …