The development of novel synthetic strategies to form new chemical entities in a
stereoselective manner is an ongoing significant objective in organic and medicinal …

The enantioselective synthesis of spirocycles has long been pursued by organic chemists.
Despite their unique 3D properties and presence in several natural products, the difficulty in …

Chiral spirooxindoles are privileged heterocyclic motifs, which are widely found in natural
alkaloids and pharmaceuticals. Moreover, the construction of chiral spiro-cyclic frameworks …

The catalytic enantioselective assembly of spirocyclic molecules featuring a spiro quaternary
carbon stereocenter is currently of great interest because such privileged 3D structures are …

Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …

The spirooxindole system is the core structure of a variety of medicinal agents and natural
products. 1, 2 In fact, spirooxindole derivatives have been described with different biological …

An asymmetric organocatalytic domino oxa‐Michael/1, 6‐addition reaction of ortho‐
hydroxyphenyl‐substituted para‐quinone methides and isatin‐derived enoates has been …

A number of popular squaramide organocatalysts' acidities were determined by an
overlapping indicator method in DMSO via UV spectrophotometric titrations. The p K a …

The first catalytic asymmetric construction of a new class of bispirooxindole scaffold‐
containing tetrahydro‐β‐carboline moiety has been established through chiral phosphoric …

This review provides the authors' selection of recent publications that highlight the
increasing efforts to develop valuable organocatalytic domino/tandem/cascade reactions as …